A Research On Pharmacognostical Analysis, Phytochemical Screening And Anti-Inflammatory Activity Of Scoparia Dulcis Linn. Plant
DOI:
https://doi.org/10.53555/jaz.v45iS1.4552Keywords:
Inflammation, Scoparia dulcis L, Phtochemicals, ExtractionAbstract
The conventional medical system makes extensive use of Scoparia dulcis L. to treat liver conditions. The entire plant of Scoparia dulcis Linn. is thoroughly pharmacognomically evaluated in this work, including morphology, microscopy, physicochemical screening, and phytochemical screening. To find the phytochemicals in the S. dulcis methanol leaf extract that could be responsible for its acceptance and use, phytochemical screening was done. The anti-inflammatory properties of the extract were further examined in relation to carrageenan-induced paw edema in Wistar albino rats. The findings of extracting Scoparia dulcis L. show the presence of several components. After two hours of carrageenan administration, the 200 mg/kg and 300 mg/kg hydroalcoholic extract of Scoparia dulcis L. effectively prevented paw edema.This might be the result of a stronger inhibitory effect of the lower dose on the synthesis of bradykinin and prostaglandin. The highest percentage of edema inhibition for the Scoparia dulcis L. hydroalcoholic extract was observed at 200 and 300 mg/kg oral dosages of the extract, with corresponding values of 60.19% and 63.48%, after a 4-hour injection of carrageenan.
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Copyright (c) 2021 Meeta A. Jiladia, Uriti Sri Venkatesh, Dakshayini, Sajeeda Niketh, Shobha N, Keshamma E, Ravi S. Vaishnov, Vishal Pathak, Anil Kumar
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