Comparative Analytical Procedure Based On Protic The Solvents For The Extraction Of Antidiabitic Drug Allium Sativum

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Dr. Menda Akkulu Naidu

Abstract

One of the most prevalent non-communicable diseases in the world, diabetes mellitus (DM) lowers quality of life in people of all ages. The illness is now a worldwide public health issue that has an impact on a person's socioeconomic standing. The most important factor in obtaining active phytoconstituents from medicinal plants is selecting the right extraction technique. Variations in extraction methods impact the biological activity and production of phytocomponents. In this research work, we observed the comparative analytical procedure based on protic solvents such as ethanol and water for the extraction of antidiabitic drugsAllium sativum. The extraction yields a much higher phenolic, saponin, and tannin content in addition to a much higher overall extract yield.


 

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How to Cite
Dr. Menda Akkulu Naidu. (2024). Comparative Analytical Procedure Based On Protic The Solvents For The Extraction Of Antidiabitic Drug Allium Sativum. Journal of Advanced Zoology, 45(2), 8–16. https://doi.org/10.53555/jaz.v45i2.3746
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Articles
Author Biography

Dr. Menda Akkulu Naidu

Associate Professor, Faculty of Pharmacy, Mandsaur University, Rewas Dewda Road, SH - 31, Mandsaur, Madhya Pradesh- 458001, India

References

M.S. Grozavescu, M. Butnariu, “Biochemical aspects of diabetes mellitus” J Diabetes Res Rev Rep, 3 (2) (2021), pp. 1-7

https://www.medschool.lsuhsc.edu/genetics/docs/DIABETES.pdf

https://www.google.com/search?q=diabetes&sca_esv=577601299&rlz=1C1JJTC_enIN1073IN1073&tbm=isch&sxsrf=AM9HkKk1LbSsOROSVpB1j48YlMIywI9tyQ:1698582061021&source=lnms&sa=X&ved=2ahUKEwi0pfmin5uCAxXkZmwGHVFbAewQ_AUoAXoECAIQAw&biw=1366&bih=651&dpr=1#imgrc=bjNKBmi3D7ZCNM

https://www.researchgate.net/publication/346963365_Solvent

https://www.google.com/search?q=protic+solvents+examples&tbm=isch&ved=2ahUKEwjvjtmNpJuCAxW9bWwGHcVEA9oQ2cCegQIABAA&oq=protic+solvents+ex&gs

https://acikders.ankara.edu.tr/pluginfile.php/158225/mod_resource/content/1/EXTRACTION_Week13.pdf

https://www.google.com/imgres?imgurl=https%3A%2F%2Fwww.planetayurveda.com%2Fpa-wp-images%2Fgarlic-cloves.

https://www.aidic.it/cet/17/56/292.pdf

https://www.google.com/url?sa=i&url=https%3A%2F%2Fwww.sciencedirect.com%2Ftopics%2Fengineering%2Fsolvent-evaporation

https://www.researchgate.net/publication/282945292_AllicinRich_Extract_Obtained_from_Garlic_by_Pressurized_Liquid_Extraction_Quantitative_Determination_of_Allicin_in_Garlic_Samples#:~:text=Pressurized%20liquid%20extraction%20(PLE)%20is,ethanol%20as%20solvent%2C%20was%20performed.

https://www.google.com/search?q=type+2+diabetes+symptoms&source=lmns&bih=639&biw=1350&rlz=1C1JJTC_enIN1073IN1073&hl=en&sa=X&ved=2ahUKEwjozu3zyfuDAxWctGMGHfIbAyQQ0pQJKAB6BAgBEAI

https://www.google.com/url?sa=i&url=https%3A%2F%2Fquizlet.com%2F566152465%2Fpp-unit-1-diabetes-flash-cards%2F&psig=AOvVaw0u0vC8XTzb-YuRzaCcqb9g&ust=1706376235113000&source=images&cd=vfe&opi=89978449&ved=0CBMQjRxqFwoTCNinpYbJ-4MDFQAAAAAdAAAAABAQ

https://www.chihealth.com/en/services/primary-care/diabetes/type-2-diabetes.html

Bayan L., Koulivand P. H., Gorji A. Garlic: a review of potential therapeutic effects. Avicenna journal of phytomedicine . 2014;4(1):1–14.

https://www.britannica.com/science/steam-distillation

Onyeagba R. A., Ugbogu O. C., Okeke C. U., Iroakasi O. Studies on the antimicrobial effects of garlic (Allium sativum Linn), ginger (Zingiberofficinale Roscoe) and lime (Citrus aurantifolia Linn) African Journal of Biotechnology . 2004;3(10):552–554. doi: 10.5897/ajb2004.000-2108.

https://www.google.com/imgres?imgurl=https%3A%2F%2Fwww.shimadzu.eu%2Fsites%2Fshimadzu.seg%2Ffiles%2Fsites%2Ffiles%2Fpr_a-eng-18009_uv-1900_figure

Perelló A., Gruhlke M., Slusarenko A.J. Effect of garlic extract on seed germination, seedling health, and vigour of pathogen-infested wheat. J. Plant Prot. Res. 2013;53:317–323.

https://www.google.com/imgres?imgurl=https%3A%2F%2Fwww.researchgate.net%2Fpublication%2F269115044%2Ffigure%2Ffig4%2FAS%3A340767341072389%401458256673302%2FChemical-structure-of-allicin-and-mechanism-of-formation-from-alliin-by-the

Benavides G. A., Squadrito G. L., Mills R. W., et al. Hydrogen sulfide mediates the vasoactivity of garlic. Proceedings of the National Academy of Sciences . 2007;104(46):17977–17982. doi: 10.1073/pnas.0705710104.