A Systematic Review On Consequential Interventions Of Mucuna Pruriens In Male Infertility
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Abstract
There are several possible contributing factors to the complex illness process that underlies male infertility. In order to treat the infertility we are experimenting on the seeds of a medicinal plant – Mucunapruriens, a tropical legume of Fabaceae family also known as Velvet beans. It is used to change the biochemical levels and semen profiles in infertile men's seminal plasma. Levodopa, also known as L-dopa and a precursor to dopamine, is found naturally in it. The experimental evidences suggest that infertile subjects treated with M. Pruriens seed powder (at a dose of 5g per day) orally were showed effective recovery. L-dopa recovers spermatogenic loss by combating ROS or reprogramming mitochondrial metabolism. Infertile men treated with M. pruriens showed decreased levels of FSH and prolactin and increased levels of testosterone, LH, dopamine, adrenaline, and noradrenalin. Men who were infertile showed a considerable improvement in their sperm count and motility. However, it also inhibits lipid peroxidation, elevated Spermatogenesis with decreased seminal plasma glutathione (GSH), SOD and elevated ascorbic acid content. It is used as Aphrodisiac that enhances sexual desire and improves conjugal relationships. On the other hand, studies suggested that M. pruriens helps in regulation of anti-oxidant defense system and works efficiently on stress management.
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