Evaluation Of Haemolytic Potential, Cytotoxic Effect And Anti-Proliferative Property Of Boerhavia Diffusa (Linn) Root Extract Using Hela Cell Line By Clonogenic Assay
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Abstract
Plant origin natural compounds believed to be safe for human have received much attention all over the world in the recent years. In ayurveda and unani medicine, different parts of the renowned herbal medicinal plant Boerhavia diffusa have been used for treating several human disorders. But very little is known about the antiproliferative activity of B. diffusa root extract. Hence investigation was carried out on the growth inhibitory property of B. diffusa on HeLa cell line. Results showed maximum of 28.95 % of hemolysis at 320 µg/ml test concentration and good cytotoxiic effect with an IC50 value of 54.06 μg/ml inhibition on HeLa cell line. The present research work using the ethanolic extract of B. diffusa root has demonstrated the antiproliferative property on HeLa cell line.
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References
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