Research Paper Evaluation of Anti-Inflammatory Activity of Cassia Angustifolia Seeds Extract in Rat

Abstract

The present study was designed to perform evaluate antiinflamatory activity of seeds of Cassia angustifolia. Seed of Cassia angustifolia was extracted using methanol as solvent by soxhlet apparatus. The evaluation of antiinflamatory activity was done using carrageenan induced rat paw edema assay. The work entitled evaluation of antiinflamatory activity of seeds of Cassia angustifolia was to determine the efficacy and safety in experimental animals. Both aqueous and methanolic extract of seeds of Cassia angustifolia have shown significant reduction in inflamation in proliferative phase as indicated by decreased granuloma formation in the cotton pellet induced granuloma model in rats. The aqueous and alcoholic extract of seeds of Cassia angustifolia has shown significant decrease in preventing generation of collagen fibres, fibroblast and suppressing mucopolysaccharides.