Impact of uncontrolled diabetes on oral disease progression and healing
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Abstract
The two most prominent chronic diseases affecting people today, diabetes mellitus and periodontal disease, astonishingly, have a lot in common. Periodontitis is more common in persons with uncontrolled diabetes, according to epidemiologic data. The term "periodontitis" refers to a set of conditions that affect the alveolar bone, gingiva, root cementum, and periodontal ligament, which together make up the tooth's supporting structure. Gingivitis and periodontitis, the two most prevalent types of periodontal disorders, are defined by a host response cascade that is triggered by the presence of bacteria and results in periodontal tissue damage. Several shared predisposing variables of a genetic, microbiological, and lifestyle origin as well as the production of advanced glycation end products as a result of hyperglycaemia are thought to be the mechanisms behind the connections between diabetes mellitus and periodontal disease. Uncontrolled diabetes and the accompanying hyperglycaemia are known to have a role in the development and progression of oral disorders. Diabetes also affects normal tissue reparative responses inside the oral cavity, which can hamper healing and result in clinical problems.
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