An Experimental Models (In-Vivo and In-Vitro) Used for the Study of Antidiabetic agents

Abstract

Diabetes is divided into two main types, type 1 (insulin-dependent diabetes Mellitus) and type 2 (non-insulin dependent diabetes). About 90% worldwide diabetics have type 2 diabetes. They are different in vivo and in vitro methods for screening new diabetes drugs. Mainly in life models uses chemicals like streptozotocin, alloxan, etc. to induce diabetes in vitro methods directly demonstrate its effect on cells responsible for induction of diabetes in humans. In vitro techniques provide more accurate information and possible Mechanisms related to diabetes. Now the latest techniques of the day such as the induction of diabetes by viruses that have also been introduced proves to be a good tool in the evaluation of diabetes drugs. This review can prove it be a good tool for researchers who want to investigate the diabetes it provides a comprehensive resource on the diabetes model under one roof.