Efficacy of Phytoextracts on Female Reproduction and Impact on Diabetes Mellitus
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Abstract
Diabetes is linked to a wide range of reproductive health problems, including delayed puberty and menarche, irregular menstruation, decreased fertility, unfavorable pregnancy outcomes, and perhaps an early menopause. Depending on the age of the diabetes diagnosis, these issues may appear during puberty, later when fertility is desired, or even during the menopause transition. In the past, amenorrhea and infertility in women with type 1 diabetes were frequently brought on by central hypogonadism. Although these problems have decreased as a result of improvements in metabolic regulation and insulin therapy, they still exist. Other reproductive effects of modern diabetes therapy, like polycystic ovarian syndrome and hyperandrogenism, influenced by insulin's action on the ovaries, have also come to light. Type 2 diabetes is becoming increasingly common in young people, which suggests that more women who are of reproductive age will face difficulties getting pregnant as a result of their diabetes. Healthcare professionals need to be knowledgeable and ready to handle the difficulties of managing reproductive health issues across the lifetime as the number of young women with diabetes keeps growing. Plant-based phytoextracts have drawn interest as potential alternative therapies for controlling diabetes and enhancing reproductive outcomes. According to studies, several phytoextracts may have qualities including insulin sensitization, anti-inflammatory activity, and antioxidants that are good for female reproductive health. Understanding the interactions between female reproductive physiology and diabetes can help overall, and phytoextract supplementation may offer valuable insights into developing personalized and effective interventions to enhance reproductive outcomes and the overall well-being of women with diabetes.
This review aims to provide a comprehensive overview of the physiology of female reproduction in the context of diabetes mellitus and investigate the potential impact of phytoextract supplementation on reproductive outcomes. By synthesizing existing literature, the aim is to highlight the pathophysiological mechanisms underlying the adverse effects of diabetes on the female reproductive system and explore the potential benefits of natural plant-derived compounds in mitigating these effects
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