The Role of Periodontitis as Modifiable Risk Factor for Alzheimer’s Disease- A Recent Update

Abstract

Alzheimer’s disease (AD) is among the most common form of dementia affecting geriatric population. Various studies have been carried out to understand the etiopathogenesis of the disease. However, no definite cause has been established and thereby, there is no definite treatment/cure available for eradication of same. The solution for managing the disease is to control the risk factors or triggering factors related to progression or worsening of the condition. Among various risk factors of AD, invasion of the oral pathogens in the brain tissue due to periodontitis (PD) has been associated as risk factor. Various studies had been carried out to state an association between PD and AD. Thereby, this article will discuss most recent evidences available to claim the role of PD as modifiable risk factor in mechanism of AD.