From Plant To Pill: Investigating Prosopis Juliflora Fruit Mucilage As A Pharmaceutical Excipient Through Isolation And Physicochemical Analysis

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Yamjala Ganesh Kumar
Talele Dipali
Pankaj Mohan Pimpalshende
Rini Punathil
Karthika Gouthaman
Akshada Devendra Khetre

Abstract

This study investigates the extraction and characterization of mucilage from Prosopis juliflora fruits as a potential pharmaceutical excipient. Employing water as the extraction medium, two precipitation approaches (Acetone and 95% ethanol) were compared. Physical, chemical, and micrometric analyses, along with FTIR spectroscopy, were conducted on the mucilages, demonstrating their compliance with official pharmaceutical parameters. Notably, mucilage precipitated with acetone exhibited superior characteristics compared to ethanol. The research concludes that Prosopis juliflora fruit mucilage holds promise as a tablet binder and viscosity-modulating agent in pharmaceutical formulations, offering a cost-effective and sustainable alternative for pharmaceutical applications. Further studies, including in vivo testing and stability assessments, are warranted for comprehensive validation of its pharmaceutical utility

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How to Cite
Yamjala Ganesh Kumar, Talele Dipali, Pankaj Mohan Pimpalshende, Rini Punathil, Karthika Gouthaman, & Akshada Devendra Khetre. (2024). From Plant To Pill: Investigating Prosopis Juliflora Fruit Mucilage As A Pharmaceutical Excipient Through Isolation And Physicochemical Analysis. Journal of Advanced Zoology, 45(2), 1115–1126. https://doi.org/10.53555/jaz.v45i2.4074
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Articles
Author Biographies

Yamjala Ganesh Kumar

Pharmacy Department of Pharmacognosy & Phytochemistery, Sree Dattha Institute of Pharmacy Sheriguda Ibrahimpatnam, 501510 Telangana

Talele Dipali

School of Pharmacy, Vishwakarma University, Survey No 2,3,4 Laxmi Nagar, Kondhwa, Budruk, Pune 411048, District. Pune 411048, Maharashtra

Pankaj Mohan Pimpalshende

Hi-Tech College of Pharmacy, Chandrapur, Maharashtra, India

Rini Punathil

St.Wilfred's Institute of Pharmacy, Shedung, Panvel, Raigad- 410206

Karthika Gouthaman

St.Wilfred's Institute of Pharmacy, Shedung, Panvel, Raigad- 410206

Akshada Devendra Khetre

St.Wilfred's Institute of Pharmacy, Shedung, Panvel, Raigad- 410206

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