Evaluation of Maternal Vitamin D and Zinc Status and Nutrient Intake Among Gestational Diabetes Mothers

Main Article Content

Pallavi R
Satish A
Anees Fathima Z
Veena BM
Parepally Roja
Syeda Farha S

Abstract

Aim: The current study aims in assessing the levels of Zinc, vitamin D, and nutrient intake among GDM women.


Methods: Hospital-based case-control study with n=60 subjects grouped into cases (n=30, women diagnosed with GDM) and control (n=30, healthy pregnant women) were recruited for the study. Vitamin D and Zinc were analyzed, anthropometric measurements and dietary data were obtained. Frequency and percent were calculated for descriptive data. ANOVA was applied to compare the nutrient intake among the groups and Pearson correlation to study the correlation between vitamin D and zinc.


Results: The levels of vitamin D (32.782 ±2.56 ng/ml and 34.754 ±5.13 ng/ml) and Zinc (70.62±17.9 µg/dL and 78.56±6.82 µg/dL) was found to be at lower end, among cases. Significant positive correlation was observed for vitamin D and Zinc. Significant difference was observed for energy, protein, vitamin D, zinc, iron, and vitamin E compared to RDA.


Conclusion: Creating awareness on the importance of each nutrient and addressing the consequences of nutrient deficiencies among reproductive-age and gravid women is crucial in promoting healthy pregnancies and optimal maternal-fetal outcomes. By providing personalized nutritional counseling and emphasizing the significance of proper nutrition, women may be empowered to make informed choices and prioritize their well-being, ultimately contributing to healthier generations to come.


 

Downloads

Download data is not yet available.

Article Details

How to Cite
Pallavi R, Satish A, Anees Fathima Z, Veena BM, Parepally Roja, & Syeda Farha S. (2024). Evaluation of Maternal Vitamin D and Zinc Status and Nutrient Intake Among Gestational Diabetes Mothers. Journal of Advanced Zoology, 45(2), 1084–1092. https://doi.org/10.53555/jaz.v45i2.4062
Section
Articles
Author Biographies

Pallavi R

Department of Nutrition & Dietetics, JSS Academy of Higher Education & Research, Mysuru, Karnataka, India

Satish A

Department of Clinical Nutrition, Sri Devaraja Urs Academy of Higher Education & Research, Kolar, Tamakka, India

Anees Fathima Z

Department of Nutrition & Dietetics, JSS Academy of Higher Education & Research, Mysuru, Karnataka, India

Veena BM

Department of Nutrition & Dietetics, JSS Academy of Higher Education & Research, Mysuru, Karnataka, India

Parepally Roja

Department of Nutrition & Dietetics, JSS Academy of Higher Education & Research, Mysuru, Karnataka, India

Syeda Farha S

Assistant Professor, Department of Nutrition & Dietetics JSS Academy of Higher Education & Research Mysuru, Karnataka, India 

References

Doupis, J. (2017). Gestational diabetes from A to Z. World Journal of Diabetes, 8(12), 489-511.

Clifton‐Bligh, R. J., McElduff, P., & McElduff, A. (2008). Maternal vitamin D deficiency, ethnicity and gestational diabetes. Diabetic medicine, 25(6): 678-684.

Janus, A., Szahidewicz-Krupska, E., Mazur, G., & Doroszko, A. (2016). Insulin resistance and endothelial dysfunction constitute a common therapeutic target in cardiometabolic disorders. Mediators of inflammation, 2016.

Westermeier, F., Sáez, P. J., Villalobos-Labra, R., Sobrevia, L., & Farías-Jofré, M. (2014). Programming of fetal insulin resistance in pregnancies with maternal obesity by ER stress and inflammation. BioMed Research International, 2014.

Hirani, V., Mosdøl, A., & Mishra, G. (2008). Predictors of 25-hydroxyvitamin D status among adults in two British national surveys. British journal of nutrition, 101(5): 760-764.

Holmes, V. A., Barnes, M. S., Alexander, H. D., McFaul, P., & Wallace, J. M. (2009). Vitamin D deficiency and insufficiency in pregnant women: a longitudinal study. British Journal of Nutrition, 102(6): 876-881.

Poel, Y. H. M., Hummel, P., Lips, P. T. A. M., Stam, F., Van Der Ploeg, T., & Simsek, S. (2012). Vitamin D and gestational diabetes: a systematic review and meta-analysis. European journal of internal medicine, 23(5): 465-469.

Intakes, I. R. D. (2005). Nutrient Reference Values for Australia and New Zealand. Commonwealth Department of Health and Ageing: Australia.

Caulfield, L. E., Zavaleta, N., Shankar, A. H., & Merialdi, M. (1998). Potential contribution of maternal zinc supplementation during pregnancy to maternal and child survival. The American journal of clinical nutrition, 68(2): 499S-508S.

Caulfield, L. E., & Black, R. E. (2004). Zinc deficiency. Comparative quantification of health risks: global and regional burden of disease attributable to selected major risk factors, 1: 257-280.

Wessells, K. R., & Brown, K. H. (2012). Estimating the global prevalence of zinc deficiency: results based on zinc availability in national food supplies and the prevalence of stunting. PloS one, 7(11): e50568.

Institute of Medicine (US) Standing Committee on the Scientific Evaluation of Dietary Reference Intakes. (2000). DRI Dietary Reference Intakes: applications in dietary assessment.

Molina-López, J., del Pozo, E. P., Florea, D. I., Fernandez, C., Osso, B. Q., Zalewska, M., & Adam, V. (2016). Nutritional and methodological perspectives of zinc ions and complexes-physiological and pathological states. International journal of electrochemical science, 11(6): 4470-4496.

Guide, A. U. S. MODULE 2. Nutrition Assessment and Classification.

Babu, G. R., Das, A., Lobo, E., John, D. A., Thankachan, P., Khetrapal, S., & Murthy, G. V. S. (2021). Mid-upper arm circumference in pregnant women and birth weight in newborns as substitute for skinfold thickness: findings from the MAASTHI cohort study, India. BMC pregnancy and childbirth, 21(1): 1-11.

Sánchez-González, C. M., Castillo-Mora, A., Alvarado-Maldonado, I. N., Ortega-González, C., Martínez-Cruz, N., Arce-Sánchez, L., & Reyes-Muñoz, E. (2018). Reference intervals for hemoglobin A1c (HbA1c) in healthy Mexican pregnant women: a cross-sectional study. BMC Pregnancy and Childbirth, 18(1): 1-6.

Abbassi-Ghanavati, M., Greer, L. G., & Cunningham, F. G. (2009). Pregnancy and laboratory studies: a reference table for clinicians. Obstetrics & Gynecology, 114(6): 1326-1331.

Martadiansyah, A., Maulina, P., Mirani, P., & Kaprianti, T. (2021). Zinc serum maternal levels as a risk factor for preeclampsia. Bioscientia Medicina: Journal of Biomedicine and Translational Research, 5(7): 693-701.

Dror, D. K., & Allen, L. H. (2011). The importance of milk and other animal-source foods for children in low-income countries. Food and nutrition bulletin, 32(3): 227-243.

Barrett, H., & McElduff, A. (2010). Vitamin D and pregnancy: An old problem revisited. Best practice & research Clinical endocrinology & metabolism, 24(4): 527-539.

Pittas, A. G., & Dawson-Hughes, B. (2010). Vitamin D and diabetes. The Journal of steroid biochemistry and molecular biology, 121(1-2): 425-429.

Zhang, C., Qiu, C., Hu, F. B., David, R. M., van Dam, R. M., Bralley, A., & Williams, M. A. (2008). Maternal plasma 25-hydroxyvitamin D concentrations and the risk for gestational diabetes mellitus. PloS one, 3(11): e3753.

Chiu, K. C., Chu, A., Go, V. L. W., & Saad, M. F. (2004). Hypovitaminosis D is associated with insulin resistance and β cell dysfunction. The American journal of clinical nutrition, 79(5): 820-825.

Labriji-Mestaghanmi, H., Billaudel, B., Garnier, P. E., Malaisse, W. J., & Sutter, B. C. J. (1988). Vitamin D and pancreatic islet function I. Time course for changes in insulin secretion and content during vitamin D deprivation and repletion. Journal of endocrinological investigation, 11: 577-584.

Reichetzeder, C., Chen, H., Föller, M., Slowinski, T., Li, J., Chen, Y. P., ... & Hocher, B. (2014). Maternal vitamin D deficiency and fetal programming-lessons learned from humans and mice. Kidney and Blood Pressure Research, 39(4): 315-329.

Soheilykhah, S., Mojibian, M., Rashidi, M., Rahimi‐Saghand, S., & Jafari, F. (2010). Maternal vitamin D status in gestational diabetes mellitus. Nutrition in Clinical Practice, 25(5): 524-527.

Ota, E., Mori, R., Middleton, P., Tobe‐Gai, R., Mahomed, K., Miyazaki, C., & Bhutta, Z. A. (2015). Zinc supplementation for improving pregnancy and infant outcome. Cochrane Database of Systematic Reviews, (2).

Bo, S., Lezo, A., Menato, G., Gallo, M. L., Bardelli, C., Signorile, A., ... & Pagano, G. F. (2005). Gestational hyperglycemia, zinc, selenium, and antioxidant vitamins. Nutrition, 21(2): 186-191.

Behboudi-Gandevani, S., Safary, K., Moghaddam-Banaem, L., Lamyian, M., Goshtasbi, A., & Alian-Moghaddam, N. (2013). The relationship between maternal serum iron and zinc levels and their nutritional intakes in early pregnancy with gestational diabetes. Biological trace element research, 154: 7-13.

Most, J., Dervis, S., Haman, F., Adamo, K. B., & Redman, L. M. (2019). Energy intake requirements in pregnancy. Nutrients, 11(8): 1812.

Bao, W., Tobias, D. K., Hu, F. B., Chavarro, J. E., & Zhang, C. (2016). Pre-pregnancy potato consumption and risk of gestational diabetes mellitus: prospective cohort study. bmj, 352.

Adeney, K. L., Williams, M. A., Schiff, M. A., Qiu, C., & Sorensen, T. K. (2007). Coffee consumption and the risk of gestational diabetes mellitus. Acta obstetricia et gynecologica Scandinavica, 86(2): 161-166.

Bao, W., Tobias, D. K., Olsen, S. F., & Zhang, C. (2014). Pre-pregnancy fried food consumption and the risk of gestational diabetes mellitus: a prospective cohort study. Diabetologia, 57, 2485-2491.

Schoenaker, D. A., Soedamah-Muthu, S. S., Callaway, L. K., & Mishra, G. D. (2015). Pre-pregnancy dietary patterns and risk of gestational diabetes mellitus: results from an Australian population-based prospective cohort study. Diabetologia, 58: 2726-2735.