Assessment and Management of Atopic Dermatitis in Primary Care Settings

Main Article Content

Najlaa Mohammad Alsudairy
Shorooq Ahmed Hamzi
Eman Ahmed M Alrashed
Baraah Ahmad Aldeera
Ali Ibrahim Al Hussain
Aldhafeer Eman Saad A
Almenyan, Zahra Ali
Abdulaziz Khalid Albulaihed
Nawaf Abdullah Alshahrani
Mohammed Ibrahim Alsaeed
Al Hashim, Khadijah Yaseen A
Renad Naif Alotaibi
Abdulelah Fahad Almansour
Ghada Hamdan Nasser Alhadidi

Abstract

An increasingly common chronic inflammatory skin condition is atopic dermatitis (AD). It exhibits severe itching as well as recurring eczematous lesions. New difficulties for treatment selection and approach occur with the expansion of available therapy alternatives for healthcare professionals and patients.  The article highlights recent developments in scientific research on atopic dermatitis diagnosis and assessment that have led to the identification of novel therapeutic targets and the development of targeted therapies, both of which have the potential to completely change the way AD is treated, particularly in a primary care setting.

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How to Cite
Najlaa Mohammad Alsudairy, Shorooq Ahmed Hamzi, Eman Ahmed M Alrashed, Baraah Ahmad Aldeera, Ali Ibrahim Al Hussain, Aldhafeer Eman Saad A, Almenyan, Zahra Ali, Abdulaziz Khalid Albulaihed, Nawaf Abdullah Alshahrani, Mohammed Ibrahim Alsaeed, Al Hashim, Khadijah Yaseen A, Renad Naif Alotaibi, Abdulelah Fahad Almansour, & Ghada Hamdan Nasser Alhadidi. (2023). Assessment and Management of Atopic Dermatitis in Primary Care Settings. Journal of Advanced Zoology, 44(S3), 1579–1585. https://doi.org/10.53555/jaz.v44iS3.1926
Section
Articles
Author Biographies

Najlaa Mohammad Alsudairy

Assistant Consultant FM, National Guard Hospital, King Abdulaziz Medical City, SCOHS, Jeddah, Saudi Arabia.

Shorooq Ahmed Hamzi

Faculty of Medicine, Jazan University, Saudi Arabia. 

Eman Ahmed M Alrashed

King Faisal university, KSA. 

Baraah Ahmad Aldeera

Buraydah Central Hospital, KSA. 

Ali Ibrahim Al Hussain

Dammam Medical complex, Dammam, KSA. 

Aldhafeer Eman Saad A

Imam Abdulrahman bin Faisal Hospital, KSA.

Almenyan, Zahra Ali

Primary care centers (Qatif health network) Eastern health cluster, KSA. 

Abdulaziz Khalid Albulaihed

Tuwaiq primary health care, Riyadh cluster, Riyadh, KSA. 

Nawaf Abdullah Alshahrani

Tuwaiq primary health care, Riyadh cluster, Riyadh, KSA. 

Mohammed Ibrahim Alsaeed

King Abdulaziz hospital, AlAhsa, KSA. 

Al Hashim, Khadijah Yaseen A

Primary health care Al Aqrabiyah health center (khobar health network ) eastern health cluster, KSA.

Renad Naif Alotaibi

Almaarefa university. 

Abdulelah Fahad Almansour

Al Wadi Health Care Center. 

Ghada Hamdan Nasser Alhadidi

Princess Nourah Bint AbdulRahman University, KSA

References

Algrani MS, AlAfnan SS, Alharthi YH, Alotaibi MA, Alshehri AA, Altemani RF, Alsharef SM, Albalawi AS, Albalawi AS, Alaenzi YA, Alali OA. Role of Nemolizumab and Omalizumab in management of atopic dermatitis: A review. Australasian Medical Journal (Online). 2021;14(2):48-52.

Yong AM, Tay YK. Atopic dermatitis: racial and ethnic differences. Dermatologic clinics. 2017 Jul 1;35(3):395-402.

Nutten S. Atopic dermatitis: global epidemiology and risk factors. Annal Nutri Metab. 2015;66:8-16.

Pyun BY. Natural history and risk factors of atopic dermatitis in children. Allergy, asthma & immunology research. 2015 Mar 1;7(2):101-5.

Garmhausen D, Hagemann T, Bieber T, Dimitriou I, Fimmers R, Diepgen T, Novak N. Characterization of different courses of atopic dermatitis in adolescent and adult patients. Allergy. 2013 Apr;68(4):498-506.

KALTALIOGLU K. EFFECT OF CARVEDILOL APPLICATION ON ATOPIC DERMATITIS-LIKE SKIN LESIONS IN MICE. Research & Reviews in Science and Mathematics. 2022 Oct.

Liang Y, Chang C, Lu Q. The genetics and epigenetics of atopic dermatitis—filaggrin and other polymorphisms. Clinical reviews in allergy & immunology. 2016 Dec;51:315-28.

Bylund S, von Kobyletzki LB, Svalstedt M, Svensson Å. Prevalence and incidence of atopic dermatitis: a systematic review. Acta dermato-venereologica. 2020 Jun 9;100(12):320-9.

Silverberg JI. Public health burden and epidemiology of atopic dermatitis. Dermatologic clinics. 2017 Jul 1;35(3):283-9.

Whiting G, Magin P, Morgan S, Tapley A, Henderson K, Oldmeadow C, Ball J, van Driel M, Spike N, McArthur L, Scott J. General practice trainees’ clinical experience of dermatology indicates a need for improved education: a cross‐sectional analysis from the Registrar Clinical Encounters in Training Study. Australasian Journal of Dermatology. 2017 Nov;58(4):e199-206.

Croce EA, Lopes FC, Ruth J, Silverberg JI. Interventions to improve primary care provider management of atopic dermatitis: a systematic review. Pediatric Dermatology. 2021 Sep;38(5):1004-11.

Sacotte R, Silverberg JI. Epidemiology of adult atopic dermatitis. Clinics in dermatology. 2018 Sep 1;36(5):595-605.

Al-Naqeeb J, Danner S, Fagnan LJ, Ramsey K, Michaels L, Mitchell J, Branca K, Morris C, Nease DE, Zittleman L, Levy B. The burden of childhood atopic dermatitis in the primary care setting: a report from the Meta-LARC Consortium. The Journal of the American Board of Family Medicine. 2019 Mar 1;32(2):191-200.

Strom MA, Fishbein AB, Paller AS, Silverberg JI. Association between atopic dermatitis and attention deficit hyperactivity disorder in US children and adults. British Journal of Dermatology. 2016 Nov 1;175(5):920-9.

Kanwar AJ, Narang T. Adult onset atopic dermatitis: Under-recognized or under-reported?. Indian Dermatology Online Journal. 2013 Jul;4(3):167.

Chamlin SL, Chren MM. Quality-of-life outcomes and measurement in childhood atopic dermatitis. Immunology and Allergy Clinics. 2010 Aug 1;30(3):281-8.

Bickers DR, Lim HW, Margolis D, Weinstock MA, Goodman C, Faulkner E, Gould C, Gemmen E, Dall T. The burden of skin diseases: 2004: A joint project of the American Academy of Dermatology Association and the Society for Investigative Dermatology. Journal of the American Academy of Dermatology. 2006 Sep 1;55(3):490-500.

Filanovsky MG, Pootongkam S, Tamburro JE, Smith MC, Ganocy SJ, Nedorost ST. The financial and emotional impact of atopic dermatitis on children and their families. The Journal of pediatrics. 2016 Feb 1;169:284-90.

Baron SE, Cohen SN, Archer CB, British Association of Dermatologists and Royal College of General Practitioners. Guidance on the diagnosis and clinical management of atopic eczema. Clinical and experimental dermatology. 2012 May 1;37(s1):7-12.

Liu P, Zhao Y, Mu ZL, Lu QJ, Zhang L, Yao X, Zheng M, Tang YW, Lu XX, Xia XJ, Lin YK. Clinical features of adult/adolescent atopic dermatitis and Chinese criteria for atopic dermatitis. Chinese Medical Journal. 2016 Apr 5;129(07):757-62.

Eichenfield LF, Ahluwalia J, Waldman A, Borok J, Udkoff J, Boguniewicz M. Current guidelines for the evaluation and management of atopic dermatitis–a comparison of the Joint Task Force Practice Parameter and American Academy of Dermatology Guidelines. Alergologia Polska-Polish Journal of Allergology. 2017 Oct 1;4(4):158-68.

Eichenfield LF, Tom WL, Berger TG, Krol A, Paller AS, Schwarzenberger K, Bergman JN, Chamlin SL, Cohen DE, Cooper KD, Cordoro KM. Guidelines of care for the management of atopic dermatitis: section 2. Management and treatment of atopic dermatitis with topical therapies. Journal of the American Academy of Dermatology. 2014 Jul 1;71(1):116-32.

Frazier W, Bhardwaj N. Atopic dermatitis: diagnosis and treatment. American family physician. 2020 May 15;101(10):590-8.

Schmitt J, Langan S, Deckert S, Svensson A, von Kobyletzki L, Thomas K, Spuls P. Assessment of clinical signs of atopic dermatitis: a systematic review and recommendation. Journal of Allergy and Clinical Immunology. 2013 Dec 1;132(6):1337-47.

Charman CR, Venn AJ, Ravenscroft JC, Williams HC. Translating Patient‐Oriented Eczema Measure (POEM) scores into clinical practice by suggesting severity strata derived using anchor‐based methods. British Journal of Dermatology. 2013 Dec 1;169(6):1326-32.

Wong IT, Tsuyuki RT, Cresswell-Melville A, Doiron P, Drucker AM. Guidelines for the management of atopic dermatitis (eczema) for pharmacists. Canadian Pharmacists Journal/Revue des Pharmaciens du Canada. 2017 Sep;150(5):285-97.

. Nankervis H, Thomas KS, Delamere FM, Barbarot S, Rogers NK, Williams HC. Scoping systematic review of treatments for eczema.

Wiren K, Nohlgård C, Nyberg F, Holm L, Svensson M, Johannesson A, Wallberg P, Berne B, Edlund F, Lodén M. Treatment with a barrier‐strengthening moisturizing cream delays relapse of atopic dermatitis: a prospective and randomized controlled clinical trial. Journal of the European Academy of Dermatology and Venereology. 2009 Nov;23(11):1267-72.

Giam YC, Hebert AA, Dizon MV, Van Bever H, Tiongco-Recto M, Kim KH, Soebono H, Munasir Z, Diana IA, Luk DC. A review on the role of moisturizers for atopic dermatitis. Asia Pacific Allergy. 2016 Apr 1;6(2):120-8.

Zirwas MJ, Stechschulte SA. Moisturizer allergy: diagnosis and management. The journal of clinical and Aesthetic dermatology. 2008 Nov;1(4):38.

Lynde C, Barber K, Claveau J, Gratton D, Ho V, Krafchik B, Langley R, Marcoux D, Murray E, Shear N. Canadian practical guide for the treatment and management of atopic dermatitis. Journal of Cutaneous Medicine and Surgery. 2005 Jun 30.

Fatani MI, Al Sheikh AA, Alajlan MA, Alharithy RS, Binamer Y, Albarakati RG, Alenzi KA, Khardaly AM, Alomari BA, Almudaiheem HY, Al-Jedai A. National Saudi consensus statement on the management of atopic dermatitis (2021). Dermatology and Therapy. 2022 Jul;12(7):1551-75.

Bissonnette R, Papp KA, Poulin Y, Gooderham M, Raman M, Mallbris L, Wang C, Purohit V, Mamolo C, Papacharalambous J, Ports WC. Topical tofacitinib for atopic dermatitis: a phase IIa randomized trial. British journal of dermatology. 2016 Nov 1;175(5):902-11.

Schneider L, Tilles S, Lio P, Boguniewicz M, Beck L, LeBovidge J, Novak N, Bernstein D, Blessing-Moore J, Khan D, Lang D. Atopic dermatitis: a practice parameter update 2012. Journal of Allergy and Clinical Immunology. 2013 Feb 1;131(2):295-9.

Gori N, Chiricozzi A, Malvaso D, D’Urso DF, Caldarola G, De Simone C, Peris K. Successful combination of systemic agents for the treatment of atopic dermatitis resistant to dupilumab therapy. Dermatology. 2021 Jan 21;237(4):535-41.

Mastorino L, Rosset F, Gelato F, Ortoncelli M, Cavaliere G, Quaglino P, Ribero S. Chronic pruritus in atopic patients treated with dupilumab: Real life response and related parameters in 354 patients. Pharmaceuticals. 2022 Jul 17;15(7):883.

Nezamololama N, Fieldhouse K, Metzger K, Gooderham M. Emerging systemic JAK inhibitors in the treatment of atopic dermatitis: a review of abrocitinib, baricitinib, and upadacitinib. Drugs in context. 2020;9.

Simpson EL, Sinclair R, Forman S, Wollenberg A, Aschoff R, Cork M, Bieber T, Thyssen JP, Yosipovitch G, Flohr C, Magnolo N. Efficacy and safety of abrocitinib in adults and adolescents with moderate-to-severe atopic dermatitis (JADE MONO-1): a multicentre, double-blind, randomised, placebo-controlled, phase 3 trial. The Lancet. 2020 Jul 25;396(10246):255-66.

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