Role Of Live Microorganisms In Colon Cancer- A Review On Probiotic Effect
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Abstract
The gut microflora plays important role in maintaining homeostasis in the
human body. An unwanted disturbance in the gut microbiome can lead to
pro-inflammatory immune responses and the initiation of disease processes,
including cancer. Literature has recently highlighted the enormous scientific
interest on the relationship between the gut microbiota and colon cancer, and
how the use of some selected probiotics can have a future impact on the
adverse events which occur during this disease. Studies prove that some
strains of probiotics can be used for by modulating intestinal microbiota and
immune response and can be an alternative healthy way to prevent for cancer
or/and as adjuvant treatment during anticancer chemotherapy. This review
presents the latest advances in research into the effectiveness of probiotics
in the prevention and treatment support of cancer. The described issues
concern to the anticancer activity of probiotic microorganisms and their
metabolites. In addition, we described the potential mechanisms of
probiotic, how they can contribute in cancer prevention. The aim of this
review was to summarize the knowledge about the effect of probiotic
microorganisms in well-balanced way to prevent colon cancer and the
adverse effects caused by related therapies
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