Black Pepper Being A Potent Anti-Carcinogen- A Short Review
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Abstract
Black pepper (Piper nigrum), sometimes referred to as the "King of Spices"
in India, is a natural product that is well-known for its capacity to target cancer
cells and serve as a source of bioactive chemicals. For several cancer cell
lines, animal models, human leukaemia cell lines, K-562 cells, and other
cancer cell lines, the two main active ingredients, piperine and piperidine,
have anti-cancer potential. According to reports, piperine has the ability to
treat cancers of the breast, ovary, stomach, lung, prostrate, rectal, cervical,
and leukemic types. Black pepper's main component, piperidine, a possible
therapeutic drug, has also been linked to ovarian, breast, colon, lung, and
prostate cancer prevention. These two plant chemicals, piperine and
piperidine, prevent cell migration, which aids in cell cycle arrest and prevents
the proliferation of cancer cells. According to reports, piperine's interaction
with DNA causes a decrease in mutagens. The anti-cancer effects of black
pepper and the likely processes by which it functions as an anti-carcinogen,
as well mentioned in the literature, are the subjects of the current review
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