Synthesis of (1-(2-((5-(4-Substitutedphenyl) Furan/Thiophen-2-Yl) Methylene) Hydrazineyl)-3-(4-Hydroxyphenyl)-1-Oxopropan-2-Yl)-4-(1H-Indol-3-Yl) Butanamide and It’s Pharmacological Studies
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Abstract
A series of (1-(2-((5-(4-substitutedphenyl) furan/thiophen-2-yl) methylene) hydrazineyl)-3-(4-hydroxyphenyl)-1-oxopropan-2-yl)-4-(1H-indol-3-yl) butanamide is synthesised and screened for antinflammatory activity by using Dexamethasone as a standard drug. Among the Screened derivatives bromine substituted and methyl substituted derivatives showed higher activity than other derivatives.
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Shilpa A.S, & Satish Kumar.M. (2023). Synthesis of (1-(2-((5-(4-Substitutedphenyl) Furan/Thiophen-2-Yl) Methylene) Hydrazineyl)-3-(4-Hydroxyphenyl)-1-Oxopropan-2-Yl)-4-(1H-Indol-3-Yl) Butanamide and It’s Pharmacological Studies. Journal of Advanced Zoology, 44(S5), 1978–1984. https://doi.org/10.17762/jaz.v44iS-5.1573
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