Comparative Study of Endovenous Laser Ablation and Sclerotherapy for the Treatment of Lower Limb Varicose Veins

Abstract

Objective: The comparison of endovenous laser ablation (EVLA) with sclerotherapy for the treatment of varicose veins in the lower limbs will focus on their efficacy, safety, patient-reported results, and cost-effectiveness. Methods: 190 suitable patients with symptomatic lower limb varicose veins were divided into the EVLA and sclerotherapy groups at random. Age, gender, and patterns of venous insufficiency were noted as baseline parameters. Reduced severity of varicose veins (CEAP classification), patient-reported improvement (VCSS and AVVQ scores), and adverse events were the primary end measures. Cost-effectiveness analysis and quality of life (EQ-5D scores) were secondary goals. Results: Sclerotherapy and EVLA both reduced the severity of varicose veins and enhanced patient-reported results. The majority of adverse events were minor and comparable between groups. Both groups had a marked improvement in quality of life. According to a cost-effectiveness analysis, EVLA might have a marginally better long-term value than sclerotherapy. Conclusion: For lower limb varicose veins, EVLA and sclerotherapy are both safe and effective treatment options, with comparable results in terms of symptom reduction and quality of life enhancement. Individual patient features, preferences, and the availability of healthcare resources should all be taken into account when deciding between these treatment modalities, with cost-effectiveness somewhat favouring EVLA. To determine the therapy outcomes' long-term viability, more investigation is required.