Association Between Mean Platelet Volume and Cardiac Troponin I in Patients with Suspected Acute Coronary Syndrome: A Diagnostic Efficiency Study

Abstract

Acute Coronary Syndrome (ACS) is a serious illness that demands prompt diagnosis. Although it may have certain drawbacks, cardiac troponin I (cTnI) has changed the diagnosis of ACS. A routine component of complete blood counts, mean platelet volume (MPV), has shown promise as a biomarker for cardiovascular disorders. The purpose of this study was to determine if MPV and cTnI levels correlate in patients who have been admitted with suspected acute coronary syndrome (ACS) and to assess the effectiveness of MPV as a diagnostic tool for ACS.

Methods: A 500 patient prospective cohort study with probable ACS was carried out. MPV and cTnI levels were evaluated, and Receiver Operating Characteristic (ROC) analysis was used to evaluate the diagnostic efficacy. Analyses of subgroups based on clinical and demographic traits were been out.

Results: cTnI levels and MPV showed a substantial positive connection. The best MPV cutoff value, according to ROC analysis, is 9.5 fL, which has a good level of discriminatory power (AUC = 0.75). varied patient categories may have varied MPV-cTnI associations, according to subgroup analyses.

Conclusion: MPV has potential as a supplementary diagnostic tool in ACS. Its potential clinical utility is highlighted by its relationship to cTnI levels and diagnostic precision. Validating these results and exploring the clinical ramifications of include MPV in ACS diagnosis and management require additional study.Keywords: Mean Platelet Volume, Cardiac Troponin I, Acute Coronary Syndrome, Diagnostic Efficiency, Biomarkers