A DIAGNOSTIC MARKER FOR ACUTE CORONARY SYNDROME USING MEAN PLATELET VOLUME (MPV): A COMPREHENSIVE STUDY

Abstract

Accurate diagnostic indicators are required for prompt intervention in cases of acute coronary syndrome (ACS), a global health concern. Mean Platelet Volume (MPV), sometimes disregarded in standard blood testing, has showed promise in assessing atherothrombosis risk and platelet function. In order to determine whether MPV may be used as a diagnostic tool in ACS, this study looked at how cardiac Troponin I levels related to MPV.

Methods: 96 patients were divided into two groups of 48 ACS cases and 48 non-ACS cases for an 18-month descriptive cross-sectional observational study. Statistical analyses were run to assess the connections between MPV and a number of other factors.

Results: Patients with ACS reported substantially higher MPV levels compared to those without ACS. Troponin I level had a positive association between them and MPV (p less than 0.0001), indicating that it could be a helpful prognostic marker. In ACS patients with ST-elevation and non-ST-elevation myocardial infarction, there were no discernible MPV changes (p = 0.3).

Conclusion: This study demonstrates a strong correlation between MPV and ACS. Combining MPV with established markers could improve ACS diagnoses because it is affordable and simple to measure. When MPV is incorporated into diagnostic protocols, there is a good opportunity for early ACS identification and intervention, which lowers the rates of morbidity and mortality that are related to it.