Antibacterial Activity And Cytotoxicity Of Strobilanthes Heyneanus Leaf

Abstract

The investigation of herbal plants for their antibacterial activity and cytotoxicity has gained considerable interest in recent years due to the emergence of antibiotic resistance and the need for safer alternatives to conventional drugs. Bacterial resistance to antibiotics is a growing concern globally, contributing to over 41% of infectious diseases. Herbal extract is found to be more efficient safer, and better quality drugs with improved anti-bacterial activities. The present study was aimed to evaluate the antibacterial activity and cytotoxicity of methanolic extracts of “Strobilanthes heyneanus” leaf against different gram positive (Staphylococcus aureus & Bacillus cereus) and gram negative (Escherichia coli, Pseudomonas aeruginosa, proteus mirabilis) reference bacterial strains. This study would provide valuable insights into its therapeutic potential, contributing to the development of novel herbal medicines and pharmaceutical formulations for the treatment of bacterial infections and cancer. The results indicated that the methanolic extracts of leaves have potential antibacterial, antioxidant and anticancer activity. Further studies on isolation and chemical structure determination of active compounds from these extracts are necessary for their utilization to treat infections caused by pathogenic and often multi drug resistant bacteria.