Method Development And Validation Of Gliclazide For Different Pharmaceutical Formulation And Its Network Pharmacology Study
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Abstract
Purpose: The research outlined in this manuscript focuses on the critical aspects of method development and validation for Gliclazide, a pivotal antidiabetic medication with various pharmaceutical formulations. Gliclazide plays a vital role in the management of type 2 diabetes, aiding in the regulation of blood glucose levels by stimulating insulin release from pancreatic beta cells.
Methods: The study emphasizes the importance of robust analytical methods such as UV spectrophotometric method for the accurate quantification of Gliclazide in different formulations, including immediate-release tablets, modified-release products, and combination therapies.
Results: The validity of these analytical methods via UV spectrophotometric analysis, is crucial for pharmaceutical manufacturers to ensure that their products consistently meet quality standards and comply with regulatory requirements. The manuscript also highlights the integration of network pharmacology, an emerging interdisciplinary approach that combines traditional pharmacology with computational methods, to comprehensively understand the effects of Gliclazide on biological systems. This approach provides a holistic perspective on the multifaceted interactions and mechanisms of Gliclazide within the human body.
Conclusion: Hence, the subsequent sections of this manuscript delve into the specifics of method development and validation while exploring the innovative landscape of network pharmacology in the context of Gliclazide quality control using UV spectrophotometric method and therapeutic targets
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