Design and Evaluation of Polyherbal Nanogel for The Treatment of Rheumatoid Arthritis

Abstract

A typical autoimmune condition known as rheumatoid arthritis is linked to progressive impairment, systemic problems, early death, and socioeconomic expenses. Rheumatoid arthritis has no known cause, and the prognosis is uncertain. However, new therapies with better results have been developed as a result of breakthroughs in our knowledge of the disease's aetiology. The current therapeutic approach, which reflects this advancement, involves starting intensive therapy shortly as a diagnosis is made and escalating the medication in the goal of clinical response while being guided by an evaluation of the disease condition. The medicinal industry is not an alternative to the increasing paradigm of nanotechnology, which is evoking advancements in practically all technological sectors. It has long been utilised for artificial medicine production. The emphasis today is on conventional therapies, though. This study has a considerable application in the developing field of nanomedicine because it focuses upon the nanogel preparations of conventional drugs. As the risks and shortcomings of contemporary medicine become more obvious, herbal therapies are experiencing a comeback because they are viewed as a fair and well-balanced method of therapy. The effectiveness of herbal medicines in the treatment and management of disease is demonstrated by developments in analytical and clinical studies. Herbal treatments' primary drawback is their failure to dissolve and stabilize. Newer technological developments may be able to solve the issues with herbal remedies. Nano-formulations show how modern technology and herbal medicines interact. Consequently, herbal medications' increased stability, homogeneity, low toxicity, and strong drug encapsulation capacities make them a promising candidate for innovative drug delivery systems.