Formulation Development And Pharmacological Evaluation Of Polyherbal Gel Containing Extract Of Sesbania Grandiflora Flower, Eclipta Alba L. Leaf, And Allium Cepa L. Bulb

Abstract

Even in places where access to modern medicine is available, interest in using herbal therapies has grown dramatically in recent years. Since medicinal plants are the main source of the bioactive molecules used in both conventional and modern medicine, phytochemicals and herbal medicines have recently attracted a lot of attention. In this study, polyherbal gel, including extracts of Sesbania grandiflora flower, Eclipta alba leaf, and Allium cepa bulb, will be made and tested. The ethanolic extracts were made using the maceration method. The following step included continuously swirling as each ingredient was properly mixed and the Carbopol 934 gel was made. The formulation's physical and chemical characteristics, including colour, aroma, pH, spreadability, extrudability, consistency, solubility, and washability, were assessed once it had been completed. The formulation was tested for physicochemical properties when it was finished, including colour, odour, pH, spreadability, extrudability, consistency, solubility, and washability. The formulation's further stability testing at various temperatures revealed no changes in irritancy, spreadability, or diffusion. It might therefore develop into a vehicle for effectively and conveniently using the medicinal benefits of polyherbal gel that contains extracts from the sesbania grandiflora flower, eclipta alba leaf, and allium cepa bulb.