Phytochemical Analysis of Tephrosia Purpurea and Docking analysis of ompA of Escherichia Coli with Beta Sitosterol

Abstract

Phytochemical analysis is essential for identifying bioactive compounds in medicinal plants like Tephrosia purpurea, known as "Sarpankha" or "Wild Indigo." Employing techniques like chromatography and spectroscopy reveals alkaloids, flavonoids, terpenoids, and phenolic compounds with diverse pharmacological activities. This study involves docking analysis, exploring the interaction between beta-sitosterol, a bioactive compound present in T.purpurea, and outer membrane protein A (ompA) of Escherichia coli. OmpA is vital for E. coli's virulence, and beta-sitosterol shows potential antibacterial activity, making it a significant focus for therapeutic investigations