Clinical Characteristics and Outcomes of Sepsis Patients in the Intensive Care Unit

Abstract

Sepsis is a life-threatening condition with diverse clinical presentations. Understanding the clinical characteristics and outcomes of sepsis patients in the intensive care unit (ICU) is crucial for optimizing patient care. This prospective observational study included 58 sepsis patients admitted to the ICU. Demographic, clinical, and laboratory data were collected. The “Sequential Organ Failure Assessment (SOFA)” score was used to assess organ dysfunction. Microbiological cultures and biomarkers (Procalcitonin and C-reactive protein) were analyzed. Patients were followed up until discharge or death. The study included sepsis patients 58 in the ICU. Patients exhibited elevated heart rate, leukocyte count, and SOFA scores, reflecting the severity of sepsis. Procalcitonin and C-reactive protein levels were elevated, correlating with positive culture results. Gram-negative organisms were the most commonly isolated pathogens. No significant age or gender-based differences in sepsis outcomes were observed. These findings highlight the clinical characteristics of sepsis in the ICU and the significance of biomarkers in assessing disease severity. This study provides valuable insights into the clinical characteristics and outcomes of sepsis patients in the ICU. It aligns with existing literature, emphasizing the heterogeneity of sepsis and the importance of early diagnosis and appropriate management. Procalcitonin and C-reactive protein are useful biomarkers for assessing disease severity. Further research with larger cohorts is needed to validate these findings and improve sepsis care.