Antifungal Activity Of Selenium Nanoparticle Prepared Using Clove And Lemon Grass Against Candida Albicans.

Authors

  • R. Priyanka Registration number: 152001034 Graduate student Department of pharmacology aveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University 
  • Dr. T. Lakshmi Narayanan Associate Professor Department of Pharmacology, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University,
  • Dr. S. Rajesh Kumar Professor Nanobiomedicine lab Center for Transdisciplinary Research Department of Pharmacology, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University Chennai- 600077,TN

DOI:

https://doi.org/10.53555/jaz.v43iS1.5363

Keywords:

selenium nanoparticles, anti-fungal, candida albicans, zone of inhibition

Abstract

Aim: To study the antifungal activity of selenium nanoparticles prepared using clove and lemon grass against candida albicans.

Materials and methods: Lemongrass and clove extract were used to make selenium nanoparticles, which were then verified using a UV-Visible spectrophotometer. The zone of inhibition displayed by the synthesized selenium nanoparticle against the test pathogen was quantified, and a graph was generated. The antifungal activity of the synthesized selenium nanoparticle against Candida albicans was examined by a well diffusion technique according to standard procedure.

Result: zone of inhibition for candida albicans in 100µl is 23mm. Thus showed more activity in 100 concentration than standard. In the case of 50µl candida albicans showed 16mm zone of inhibition which is less than standard. In the case of 25µl candida albicans showed 14mm of zone of inhibition which is less than standard.

 

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Published

2022-12-22

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