Impact Of Tobacco Toxins On The Lifespan Of Fruit Flies (Drosophila Melanogaster)
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Abstract
Tobacco, a extensively consumed plant recognized for its adverse health effects in humans, comprises various toxic compounds. Previous researches have solely delved into the impact of nicotine exposure on the reproductive and developmental aspects of fruit flies. Consequently, our investigation seeks to broaden the comprehension of the detrimental impacts encompassing all constituents of tobacco extract on the lifespan of fruit flies. Varied concentrations of tobacco extract (0.02, 0.04, 0.06, 0.08, and 0.1 g) were employed to establish a spectrum of exposure levels and the data included the number of fruit flies at each developmental stage in the new generation and the lifespan in each concentration group over the time. Our findings demonstrate a decline in population size within the first and second filial generations when transitioning from a normal condition to a high concentration of tobacco. Furthermore, our results reveal an inverse relationship between pupa size and tobacco concentration, resulting in smaller fruit flies when exposed to higher concentrations of tobacco extract. This suggests a detrimental impact of tobacco toxins on the embryonic development and overall well-being of fruit flies. The implications of our study extend to a broader understanding of potential risks associated with tobacco exposure in various organisms, including humans.
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References
Hoffmann, D., & Hoffmann, I. 1997. The changing cigarette, 1950–1995. Journal of Toxicology and Environmental Health, 50(4), 307-364.
Bier, E. 2005. Drosophila, the golden bug, emerges as a tool for human genetics. Nature Reviews Genetics, 6(1), 9-23.
Chell, J. M., & Brand, A. H. 2010. The Drosophila cholinergic system. In International Review of Neurobiology, 93: 307-336. Academic Press.
Rohwedder, A., Selcho, M., Chassalevris, T., & Thum, A. S. 2007. Neuropeptide F in Drosophila melanogaster. Peptides, 28(6), 1884-1893.
Boffetta, P., Straif, K. 2009. Use of smokeless tobacco and risk of myocardial infarction and stroke: systematic review with meta-analysis .BMJ, 342, d2040.
Irene Miguel-Aliaga, Heinrich Jasper, Bruno Lemaitre. 2018. Anatomy and Physiology of the Digestive Tract of Drosophila melanogaster. Genetics 210 (2), 357-396, 2018
Athanasios-Stefanos Giannopoulos, Lydia Giannakou, Natalia Gourgoulianni et al. 2023. The effect of cigarette smoke extract exposure on the size and sexual behaviour of Drosophila melanogaster. Environmental Toxicology and Pharmacology 104, 104325.
Aditi Dosi, Jennifer Lambert-Peloquin.Exploring. the Effects of E-Cigarettes using Drosophila Melanogaster. 2021. Journal of Student Research 10 (3).
WANG Fu-gang et al. 2010. Effect of Aqueous Solution of Cigarette Smog on the Fecundity of Male Fruit Flies. Journal of Anhui Agri. 38(24): 12958,12960.
Firzan Nainu, Yoshinobu Nakanishi, Akiko Shiratsuchi. 2019.Fruit fly as a model organism in the study of human diseases and drug discovery J. Cent. Med. Educ. Sapporo Med. Univ 10, 21-32.