Facing The Menace Of Bioterrorism: Actualities, Hurdles, And Safeguarding Approaches

Main Article Content

Dr Pramjit Singh

Abstract

Global terrorism poses an escalating peril to global stability, heightening the spectre of bioterrorism. This analysis delves into the conceivable menace of bioterrorism, the exploitable agents involved, and recent advancements in technologies and policies aimed at detecting and managing deliberately initiated epidemics. The response, both local and international, to infectious disease outbreaks, such as severe acute respiratory syndrome and the West African Ebola virus epidemic, laid bare significant deficiencies that could be exploited by bioterrorists instigating an epidemic intentionally. Prioritizing the development of novel vaccines and antimicrobial treatments, alongside expediting clinical trials through innovative methodologies, remains imperative. Enhanced measures are warranted to safeguard healthcare personnel operating in hazardous settings, particularly in regions lacking adequate infrastructure. Novel and refined strategies should be devised for surveillance, early detection, prompt response, efficient patient isolation, control of potentially infected individuals' movements, and effective risk communication. Prudent regulation of access to hazardous pathogens is essential, ensuring progress in countermeasure development is not hindered. It is deduced that readiness for deliberate outbreaks not only fortifies preparedness for natural epidemics but also reciprocally enhances it.

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How to Cite
Dr Pramjit Singh. (2024). Facing The Menace Of Bioterrorism: Actualities, Hurdles, And Safeguarding Approaches. Journal of Advanced Zoology, 45(2), 1535–1543. https://doi.org/10.53555/jaz.v45i2.4442
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Articles
Author Biography

Dr Pramjit Singh

Research Assistant, Defence & Strategic Studies, M.D. University, Rohtak, Haryana

References

Carus, WS. (2015). The history of biological weapons use: What we know and what we don't. Health Secur.

Tumpey, TM., Basler, CF., Aguilar, PV., Zeng, H., Solórzano, A., Swayne, DE., et al. (2005). Characterization of the reconstructed 1918 Spanish influenza pandemic virus. Science.

Tucker, JB. (2009). Strategies to Prevent Bioterrorism: Biosecurity Policies in the United States and Germany. Biosecurity: Origins, Transformations and Practices.

Nixdorff, K., Brauburger, J., & Hahlbohm, D. (2000). The Biotechnology Revolution: The Science and Applications. In: Dando M.R, Pearson G.S, Toth T (Eds.), Verification of the Biological and Toxin Weapons Convention. NATO ASI Series (Series 1: Disarmament Technologies) Vol. 32. Springer.

Jefferson, C., Lentzos, F., & Marris, C. (2014). Synthetic biology and biosecurity: Challenging the "myths." Front Public Health.

Fraser, CM., & Dando, MR. (2001). Genomics and future biological weapons: The need for preventive action by the biomedical community. Nat Genet.

Williams, JH., Phillips, TD., Jolly, PE., Stiles, JK., Jolly, CM., & Aggarwal, D. (2004). Human aflatoxicosis in developing countries: A review of toxicology, exposure, potential health consequences, and interventions. Am J Clin Nutr.

Peters, KM. (2001). Behind in the biowar. Government Executive.

Greenwood, D. (2012). Medical Microbiology, with Studentconsult Online Access, 18: Medical Microbiology. Elsevier Health Sciences.

Mukunda, G., Oye, KA., & Mohr, SC. (2009). What rough beast? Synthetic biology, uncertainty, and the future of biosecurity. Politics Life Sci.

Klotz, LC., & Sylvester, EJ. (2009). Breeding Bio Insecurity: How US Biodefense is Exporting Fear, Globalizing Risk, and Making us all Less Secure. University of Chicago Press.

van Aken, J., & Hammond, E. (2003). Genetic engineering and biological weapons. New technologies, desires and threats from biological research. EMBO Rep.

Kolkman, JA., & Stemmer, WP. (2001). Directed evolution of proteins by exon shuffling. Nat Biotechnol.

Terwilliger, JD., & Göring, HH. (2009). Gene mapping in the 20th and 21st centuries: Statistical methods, data analysis, and experimental design. Human biology.

Relman, DA. (2006). Bioterrorism-preparing to fight the next war. N Engl J Med.

Simon, JD. (1997). Biological terrorism. Preparing to meet the threat. JAMA.

Franz, DR., & Zajtchuk, R. (2002). Biological terrorism: Understanding the threat, preparation, and medical response. Dis Mon.

Chameau, JL., Ballhaus, WF., & Lin, H. (2014). Emerging and Readily Available Technologies and National Security: A framework for Addressing Ethical, Legal, and Societal Issues. The National Academies Press.

Sayler, GS., & Ripp, S. (2000). Field applications of genetically engineered microorganisms for bioremediation processes. Curr Opin Biotechnol.

van Aken, J., & Hammond, E. (2002). Closing loopholes in the biological weapons convention. Med Confl Surviv.

Glazer, AN., & Nikaido, H. (2007). Microbial Biotechnology: Fundamentals of Applied Microbiology. Society for Industrial Microbiology, Cambridge University Press.

Zilinskas, RA. (2000). Biological Warfare: Modern Offense and Defense. Lynne Rienner Publishers.

von Nussbaum, F., Brands, M., Hinzen, B., Weigand, S., & Häbich, D. (2006). Antibacterial natural products in medicinal chemistry-exodus or revival? Angew Chem Int Ed Engl.

Pearson, GS. (2001). New Scientific and Technological Developments of Relevance to the Fifth Review Conference. Review Conference Paper.

Direko, M. (2011). Genome Assembly of Next-Generation Sequencing Data for the Oryx Bacillus: Species of the Mycobacterium tuberculosis Complex.

Hauskeller, C. (2006). Human Genomics as Identity Politics. University of Exeter.

Block, SM. (1999). Living Nightmares: Biological Threats Enabled by Molecular Biology. In: The New Terror: Facing the Threat of Biological and Chemical Weapons.

Cho, MK., Magnus, D., Caplan, AL., & McGee, D. (1999). Ethical considerations in synthesizing a minimal genome. Science.

Liu, MA. (2011). DNA vaccines: An historical perspective and view to the future. Immunol Rev.

Jorde, LB., Watkins, WS., Bamshad, MJ., Dixon, ME., Ricker, CE., Seielstad, MT., et al. (2000). The distribution of human genetic diversity: A comparison of mitochondrial, autosomal, and Y-chromosome data. Am J Hum Genet.

Smart, JK. (1997). History of chemical and biological warfare: An American perspective. In: Medical Aspects of Chemical and Biological Warfare. Office of the Surgeon General.

Cooper, M. (2006). Pre-empting emergence: The biological turn in the war on terror. Theory Culture Soc.

Enderle, J., & Bronzino, J. (2012). Expression of cereolysine AB genes in Bacillus anthracis vaccine strain ensures protection against experimental hemolytic anthrax infection. Introduction to biomedical engineering.

Cello, J., Paul, AV., & Wimmer, E. (2002). Chemical synthesis of poliovirus cDNA: Generation of infectious virus in the absence of natural template. Science.

Rosengard, AM., Liu, Y., Nie, Z., & Jimenez, R. (2002). Variola virus immune evasion design: Expression of a highly efficient inhibitor of human complement. Proc Natl Acad Sci U S A.

Phillips, CJ., Harrington, AM., Yates, TL., Simpson, GL., & Baker, RJ. (2009). Global Disease Surveillance, Emergent Disease Preparedness, and National Security. Museum of Texas Tech University.

Kyrikou, I., & Briassoulis, D. (2007). Biodegradation of agricultural plastic films: A critical review. J Polymers Environ.

Després, V., Huffman, JA., Burrows, SM., Hoose, C., Safatov, A., Buryak, G., et al. (2012). Primary biological aerosol particles in the atmosphere: A review. Tellus B: Chem Phys Meteorol.

Miller, S., & Selgelid, MJ. (2007). Ethical and philosophical consideration of the dual-use dilemma in the biological sciences. Sci Eng Ethics.

Carlson, R. (2009). The changing economics of DNA synthesis. Nat Biotechnol.

Wright, GD. (2010). Antibiotic resistance in the environment: A link to the clinic? Curr Opin Microbiol.

Dennis, C. (2001). The bugs of war. Nature.

Hall, V., Johnson, D., & Torresi, J. (2018). Travel and biologic therapy: Travel-related infection risk, vaccine response and recommendations. Journal of travel medicine.