Formulation And Evaluation Of Karanj Silver Nanoparticle Gel

Main Article Content

Miss. Shraddha U. Kothmire
Dr. Mrs. Shilpa Chaudhari
Mr. Mohit Mahajan
Mr. Abhishek Nemmanivar

Abstract

Pongamia pinnata Linn.( Aka Karanja in Ayurveda) is a rough tree and a traditionally used medicinal factory set up throughout the India. It's generally used in Ayurveda and has an immense eventuality in treating colorful skin conditions like eczema, psoriasis, itchy skin, infections of skin. The end of present study was to prepare tableware nanoparticle herbal gel expression containing methanolic excerpt of Karanj on psoriasis. Topical gel expression was designed by using methanolic excerpt of seeds of pongamia pinnata in varied attention. The gel was prepared by using tableware nitrate, chitosan, carbopol 934, Pongamia Pinnata Extract( KARANJ), Methanol, propylene glycol, methyl paraben, propyl paraben,triethanolamine, glycerin and needed quantum of distilled water. The set gels were estimated for medicine content, pH, spread capability, physical appearance, density, swelling indicator, prolixity study, unity and grit. The results prove that gel phrasings were good in appearance and unity.

Downloads

Download data is not yet available.

Article Details

How to Cite
Miss. Shraddha U. Kothmire, Dr. Mrs. Shilpa Chaudhari, Mr. Mohit Mahajan, & Mr. Abhishek Nemmanivar. (2024). Formulation And Evaluation Of Karanj Silver Nanoparticle Gel. Journal of Advanced Zoology, 45(3), 448–464. https://doi.org/10.53555/jaz.v45i3.4344
Section
Articles
Author Biographies

Miss. Shraddha U. Kothmire

Dr. D. Y. Patil College of Pharmacy, Akurdi, Pune, India 411044

 

Dr. Mrs. Shilpa Chaudhari

Department of pharmaceutics, Dr. D.Y. Patil college of Pharmacy, Akurdi, Pune-411044, Maharashtra, India.

Mr. Mohit Mahajan

Department of pharmaceutics, Dr. D.Y. Patil college of Pharmacy, Akurdi, Pune-411044, Maharashtra, India.

Mr. Abhishek Nemmanivar

Department of pharmaceutics, Dr. D.Y. Patil college of Pharmacy, Akurdi, Pune-411044, Maharashtra, India

References

Hahens WI., Oomen AG., DeJong WH., Cassee FR. What do we (need to) know about the kinetic properties of nanoparticles in the body? Regulatory Toxicology and Pharmacology. 2007; 49:217-229.

Gaur A., Mindha A., Bhatiya AL. Nanotechnology in Medical Sciences. Asian Journal of Pharmaceutics. 2008; 80-85.

M. A. Giri1 , A. C. Abhale1 , M. R. Ahire1 , Rasika D. Bhalke, Formulation, Characterization, and Evaluation of Topical Anti-inflammatory Herbal Gel. International Journal of Pharmaceutical & Biological Archives 2019; 10(3):190-195

Salomy Monica*, and J. Gautami, DESIGN AND EVALUATION OF TOPICAL HYDROGEL FORMULATION OF DICLOFENAC SODIUM FOR IMPROVED THERAPY. IJPSR (2014), Vol. 5, Issue 5

*Okafo S.E.1 , Iwetan B.B.2 , Odiri O.O.1 , Nwankwo L.U. Anti-inflammatory Property of Gels Formulated using Dacryodes edulis Bark Ethanol Extract. Afr. J. Biomed. Res. Vol. 25 (September 2022); 413 – 418

KUSHWAHA ALKA 1 , BANI SHASHIKALA B 2. ANALYTICAL STUDY OF BAKUCHI Psoralia corylifolia LIN. Research Article International Ayurvedic Medical Journal ISSN:2320 5091

Illango R, Jayakar B, Kavimani S. Chitosan as a new pharmaceutical Excipient. The Eastern Pharmacist. 1998; p.47-49.

Agnieszka Kulawik-Pióro Plant and Herbal Extracts as Ingredients of Topical Agents in the Prevention and Treatment Radiodermatitis

S. KATEKHAYE*, M. S. KALE AND K. S. LADDHA. Development and Validation of an HPLC Method for Karanjin in Pongamia pinnata linn.

Jian-Ru Guo, Qian-Qian Chen, Christopher Wai-Kei Lam and Wei Zhang. Effects of karanjin on cell cycle arrest and apoptosis in human A549, HepG2 and HL-60 cancer cells.

Mohini. Phanse* , a Parag Kulkarni, a Shailesh Kewatkar, aMeghana Lande, a Santosh Bhujbal, b Pravin Chaudhari. Evaluation of anti-inflammatory activity of herbal gel formulation. J. Nat. Prod. Plant Resour., 2011, 1 (2): 25-28

Alfia Sheikh, Aayush Pathak, Charu Bante, Ankita Gedam, Ashvin Sonwane, Apeksha Gharjare, Poonam Bhange. “FORMULATION AND EVALUTATION OF HERBAL GEL OF ALOE VERA, AZADIRACHTA INDICA AND LYCOPERSICONESCULANTUM EXTRACT”

Edakulathur Richu*, Wani Sneha, Bhagyashree S. Mundhe, Saurabh Arun Rayate, Aishwarya Sahebrao, Talale Swati, and Jadhav Anil. FORMULATE AND EVALUATE GEL CONTAINING NANOSTRUCTURED LIPIDS OF PONGAMIA PINNATA

Evanoff, Chumanov G. Size-controlled synthesis of nanoparticles. 2. measurement of extinction, scattering, and absorption cross sections. J Phys Chem B. 2004; 108:13957– 139

Uwe Wollina1*, Michael Tirant2, Aleksandra Vojvodic3, Torello Lotti, “Treatment of Psoriasis: Novel Approaches to Topical Delivery”, Open Access Macedonian Journal of Medical Sciences. 2019 Sep 30; 7(18):3018-3025.

Gulbahar, Koca Tuba Tulay, and Baglan Tolga, A brief summary of clinical types of psoriasis, North Clin Istanb. 2016; 3(1): 79–82.

Whan B. Kim, Dana Jerome, Jensen Yeung , Diagnosis and management of psoriasis, Can Fam Physician. 2017 Apr; 63(4): 278–285.

https://www.mayoclinic.org/diseases-conditions/psoriasis/diagnosis-treatment/drc20355845

Ibrahim Khan a, *, Khalid Saeed b , Idrees Khan , Nanoparticles: Properties, applications and toxicities, Arabian Journal of Chemistry Volume 12, Issue 7, November 2019, Pages 908-931

Merga G, Wilson R, Lynn G, Milosavljevic B, Meisel D. Redox Catalysis on “naked” silver nanoparticles. J Phys Chem C. 2007; 111:12220–12206.

Vila A., Sanchez A., Tobio M., Calvo P., Alonso MJ. Design of biodegradable particles for protein delivery. Journal of Control Release. 2002; 78:15-24. http://dx.doi.org/10.1016/S0168-3659(01)00486-2

Mu L., Feng SS. A novel controlled release formulation for the anticancer drug paclitaxel (Taxol(R)), PLGA nanoparticles containing vitamin E TPGS. Journal of Control Release. 2003; 86:33-48.

Sapra P., Tyagi P., Allen TM. Ligand-targeted liposomes for cancer treatment. Current Drug Delivery. 2005; 2:369-381.

Ainley W, Weller PJ. A Handbook of pharmaceutical excipients. Pharmaceutical press, American pharmaceutical association. 2nd edition. 1994: p.71-73, 84-85, 229- 32, 28082, 362-66, 392-99.