EVALUATION OF THE IMPACT OF VARIOUS EXTRACTS OF Swertia chirata ON ANTIMICROBIAL-RESISTANT STRAINS OF PATHOGENS
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Abstract
In several Asian nations, as well as other regions of the world, the plant Swertia chirata is commonly utilized as a herbal remedy. The current study aimed to assess Swertia chirata's impact on a range of antimicrobial-resistant bacteria. To achieve this, the plant's leaves and stems were extracted using ethanol and methanol. Gram-negative bacteria (Escherichia coli) and Gram-positive bacteria (Staphylococcus aureus) were used as test organisms. The agar well diffusion method was utilized to determine the antibacterial activity and calculate the Minimum Inhibitory Concentration (MIC). Using the broth dilution procedure, MIC was determined. Bacterial sp. demonstrated a significant zone of inhibition against all extracts out of all the strains. Methanol and ethanol were employed as controls. The results indicated that the ethanol extract of the stem and leaves was superior to the methanol extract in terms of its ability to the methanol extract
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