Effect of Bael, Cinnamon and Neem Extract Mouthwashes on Dental Plaque, Gingival Health and Salivary pH among adults residing in a hostel in Chennai, India – A triple blinded, randomized controlled trial

Main Article Content

Dr. Divya Raghunathan
Dr.Preetha Elizabeth Chaly, M.D.S
Dr. Shyam Sivaswamy, M.D.S

Abstract

Aim: To assess and compare the effect of mouthwash containing 0.3% Aegle marmelos (Bael) leaves extract with other herbal mouthwashes containing 0.3% Cinnamomum zeylanicum (Cinnamon) barks extract and 0.3% Azadirachta indica (Neem) leaves extract and with 0. 2% chlorhexidine mouthwash on dental plaque, gingival health and salivary p H among adults.


Materials and Methods: A triple blinded randomized controlled trial with concurrent parallel study design was carried out. Around, 48 young adults were randomly allotted to four groups - Group A (Chlorhexidine), Group B (Cinnamon), Group C (Bael) and Group D ( Neem) by simple randomization technique. They were advised to rinse with 10 ml of their respected mouthwashes twice daily for 1 minute for a period of 28 days. The dental plaque score and gingival inflammation score were recorded using Plaque index and Gingival index at the baseline, 15th day, 22nd day and 29th day. Statistical analysis were done using ANOVA and repeated measure ANOVA for the plaque and gingival scores and Paired sample t test for p H


Results: Mouthwashes containing Bael, Neem and Chlorhexidine showed a stastistically significant reduction in the plaque levels at the end of second week (mean difference from baseline to 2nd week = 0. 158, 0. 100 and 0. 108 respectively with p value < 0. 05). However, at all the time points considered in the study, Bael was more effective in reducing the gingivitis.


Conclusion: Bael extract mouthwash is as effective as the gold standard Chlorhexidine mouthwash in reducing the plaque and gingivitis and opens new perspectives for its use

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How to Cite
Dr. Divya Raghunathan, Dr.Preetha Elizabeth Chaly, M.D.S, & Dr. Shyam Sivaswamy, M.D.S. (2024). Effect of Bael, Cinnamon and Neem Extract Mouthwashes on Dental Plaque, Gingival Health and Salivary pH among adults residing in a hostel in Chennai, India – A triple blinded, randomized controlled trial. Journal of Advanced Zoology, 45(3), 103–125. https://doi.org/10.53555/jaz.v45i3.4265
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Articles
Author Biographies

Dr. Divya Raghunathan

Assistant Professor, Department of Public Health Dentistry, Meenakshi Ammal Dental College and Hospital, Maduravoyal, Chennai, Tamil Nadu

Dr.Preetha Elizabeth Chaly, M.D.S

Head of the Department, Department of Public Health Dentistry, Meenakshi Ammal Dental College and Hospital, Maduravoyal, Chennai, Tamil Nadu

Dr. Shyam Sivaswamy, M.D.S

Present and Permanent Address – Department of Public Health Dentistry, Meenakshi Ammal Dental College and Hospital, Maduravoyal, Chennai, Tamil Nadu. Phone Number – 9940595385

Sources of support: None Prior presentation: None Word count: 4859 Adhered to the ARRIVE guidelines

References

N. Nagappan, Joseph John. Antimicrobial Efficacy of Herbal and Chlorhexidine Mouth rinse - A systematic review. JDMS. 2012; 2( 4): 5 -10

Baratakke SU, Raju R, Kadanakuppe S, Savanur NR, Gubbihal R, Kousalaya PS. Efficacy of triphala extract and chlorhexidine mouth rinse against plaque accumulation and gingival inflammation among female undergraduates: A randomized controlled trial. Indian J Dent Res. 2017; 28: 49 - 54.

Nitish Abrol, Anil Singla, Vivek Mahajan, H S Jaj, Vishal Seth and Priyanka. Organic mouthwash in comparison to Chlorhexidine mouthwash on Streptococcus mutans in early phase of orthodontic treatment. J Indian Orthod Soc. 2015; 49: 188-92.

Prabodh Chander Sharma, Vivek Bhatia, Nitin Bansal. A review of Bael tree. Nat Prod Rad. 2007; 6(2): 171 -178.

Mona Kejariwal. Evaluation of Antioxidant Potential and Phytochemical investigations on Aegle marmelos ( L.) Corr. Bull Env Pharmacol Life Sci. 2016: 5(2); 42 -52

Anshu Rani, Raj Vir Singh, S.S. Tomar and Adesh Singh. Medicinal Significance of Aegle marmelos ( Bael). International Journal of Plant Research. 2012; 25(2): 320 - 323

Biresh K Sarkar, Shailendra Singh Solanki. Isolation, characterization and antibacterial activity of leaves extract of bael ( Aegle Marmelos ). International Journal of Pharmacy & Life Sciences. 2011; 2 (12): 7 - 10

Chandra Prakash Kala. Ethnobotany and Ethnocoservation of Aegle marmelos ( L.) Correa. Indian Journal of Traditional Knowledge 2006; 5(4): 1 -5

Handbook on Medicinal and Aromatic plants. List of prioritized species of Medicinal Plants being promoted by the National Medicinal Plants Board) (Revised list) ( Internet)– Available from: http://assamagribusiness.nic.in/nedfi/map25.pdf

United States Department of Agriculture, National Resources Conservation Services Accessed from: https://plants.usda.gov/core/profile?symbol=AEMA Pholtan R Rajamanoharan. Search towards the Tamil Medical Manuscripts . 1st edition, Cultural department of Eastern province. 2016, page: 61 -63 ( Last updated on 03 August 2017)

Dhananjay Vasudeo Dwived. Bilva in Indian Tradition. Indian Journal of History of Science. 2012 : 47 ; 37 -61

Paul A. Davis and Wallace Yokoyama. Cinnamon Intake Lowers Fasting Blood Glucose: Meta- Analysis. Journal of Medicinal Food. 2011; 14( 9): 884 - 889

Pasupuleti Visweswara Rao and Siew Hua Gan. Cinnamon: A Multifaceted Medicinal Plant. Evidence- Based Complementary and Alternative Medicine. 2014; 14: 29- 42

Burt S. Essential oils: their antibacterial properties and potential applications in foods - a review. International Journal of Food Microbiology. 2004; 94: 223 - 253.

Pritima R, Pandian R. Antimicrobial potency of crude extracts of Azadirachta indica A. Juss (leaf) against microbes causing reproductive tract infections among women. Current Biotica. 2008; 2( 2): 193 -199

Anirban Chatterjee, Mini Saluja, Nidhi Singh, Abhishek Kandwal. To evaluate the antigingivitis and antipalque effect of an Azadirachta indica ( neem) mouthrinse on plaque induced gingivitis: A double‑blind, randomized, controlled trial. Journal of Indian Society of Periodontology. 2011; 15(4): 398 -401

Venugopalan Santhosh Kumar, Visweswaran Navaratnam. Neem (Azadirachta indica): Prehistory to contemporary medicinal uses to humankind. Asian Pac J Trop Biomed 2013; 3(7): 505 -514.

Gupta D, Nayan S, Tippa nawar HK, Patil GI, Jain A, Momin RK, Gupta RK. Are herbal mouthwash efficacious over chlorhexidine on the dental plaque? Phcog Res. 2015; 7: 277 -281.

Ceylane A, Daniel Y. Antimicrobial activity of spices. J Rapid Methods Autom Microbiol. 2004; 12: 1 - 55.

Sunayana Manipal, Sajjid hussain, Umesh Wadgave, Prabu Duraiswamy, K. Ravi. The Mouthwash War - Chlorhexidine vs. Herbal Mouth Rinses: A Meta- Analysis. Journal of Clinical and Diagnostic Research. 2016 May, Vol -10( 5): ZC 81 - ZC 83

Abrol N, Singla A, Mahajan V, Jaj H S, Seth V, Priyanka. Reliability of organic mouthwash in comparison to chlorhexidine mouthwash on Str eptococcus mutans in early phase of orthodontic treatment. J Indian Orthod Soc 2015; 49:188 - 92

Yeturu SK, Acharya S, Urala AS, Pentapati KC. Effect of Aloe vera, chlorine dioxide, and chlorhexidine mouth rinses on plaque and gingivitis: A randomized controlled trial. J Oral Biol Craniofac Res 2016; 6( 1): 54 -58.

Mali AM, Behal R, Gilda SS. Comparative evaluation of 0.1% turmeric mouthwash with 0. 2% chlorhexidine gluconate in prevention of plaque and gingivitis: A clinical and microbiological study. J Indian So c Periodontol 2012; 16: 386 -91

Devanand Gupta, Dara John Bhaskar, Rajendra Kumar Gupta, Bushra Karim, Ankita Jain, Rajeshwar Singh, Wahaja Karim. A randomized controlled clinical trial of Ocimum sanctum and chlorhexidine mouthwash on dental plaque and gingival inflammation. J Ayurveda Integr Med. 2014; 5(2): 109 –116.

Pradeep AR, Suke DK, Martande SS, Singh SP, Nagpal K, Naik SB. “Triphala”

- A New Herbal Mouthwash in Gingivitis: A Randomized Controlled Clinical Trial. Journal of Periodontology. 2016; 0.1902/jop.2016.130406.

Deshmukh MA, Dodamani AS, Karibasappa G, Khairnar MR, Naik RG, Jadhav HC. Comparative Evaluation of the Efficacy of Probiotic, Herbal and Chlorhexidine Mouthwash on Gingival Health: A Randomized Clinical Trial. J Clin Diagn Res 2019; 11(3): ZC 13 - ZC 16