Patients With Type II Diabetes Mellitus At A Tertiary Care Hospital: A Prospective Study On Anti-Diabetic Drug Prescribing Patterns

Abstract

The main aim is to study on prescribing patterns of anti-diabetic drugs for patients with type- II diabetes mellitus. Out of 457 patients screened, 426patients were enrolled according to inclusion and exclusion criteria. Among them 62.44% were males and 37.55% were females. The study found to be a higher incidence of diabetes among elderly patients, with a high incidence in the age group between 41-60 years (50.70%) and followed by 61‑80 years (19.24%). The study resolved that most of the patients were suffering from diabetes for 5 to 10 years, 221 (73.94%) of duration years followed by 1 to 5 years, 94 (22.06%). A total of 1565 drugs were prescribed in the overall study period. 68.62% were diabetic drugs, 13.41% hypertensive drugs, 07.85% NSAIDs, 07.66% asthmatic drugs, 03.57% antidepressants, and 04.40% supplements of drugs. The study resolved that drugs were prescribed as monotherapy was 49.76%, two drug therapy were 36.61%, three-drug therapy were 08.45% and four-drug therapy was 05.16%. In this study, 426 anti-diabetic drugs prescribed, among that, the physician’s most well-liked single-drug therapy more than multiple drug therapy and also the most often prescribed category was Biguanides category of anti-diabetic agents. Among Biguanides, Metformin was the foremost often utilized anti-diabetic drugs. The foremost prevalent combination of the drug was a two-drug therapy of Biguanides +sulfonylureas, among these combinations, Metformin + Glimipride was the foremost often utilized anti-diabetic drugs. Followed by 3 drug therapy were Biguanides +sulfonyl ureas+ thiazolidinedione and 4 drug therapies were Biguanides + sulfonylureas + DPP 4 inhibitors + thiazolidinedione.Pharmacists can contribute drastically to promote the rational use of medicines, even in resource-limited settings. This, of course, requires strong collaboration between different institutions and commitments of the pharmacists to the cause. Pharmacist medication review, patient counseling and telephone follow-up can limit the Adverse Drug Reactions. Medication discrepancies before and after discharge were common targets of intervention.