Review On Effect Of Curcumin In The Treatment Of Cancer
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Abstract
Caner is a devastating disease condition and is the second most life taking disease globally. After decades of research in this field we are still looking for therapeutical agents with the most efficacies and least toxicities. Curcumin is one of the cancer therapeutic agents that is derived from the Curcuma longa(turmeric) plant, and still in vitro and in vivo research is going on to find its beneficial effects on various cancers. Due to its potency to affect multiple targets of different cellular pathways. It is considered a promising agent to tackle various cancers alone or in combination with the existing chemotherapies. This review covers basic properties, mechanism of action, potential targets of curcumin. This study aims to evaluate the antiproliferative property of curcuminoids in three human cancer cell lines. The study consists of a) Establishing inhibition-concentration 50% (IC50), by Methyl thiazole tetrazolium (MTT) reduction method and b) Viable Cell Count by Trypan blue exclusion method.
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