“Design, Synthesis And Microbicidal Activity Of Some New N2, N4-Bis{2-(Substitutedphenyl)-3-Phenyl-1,3-Thiazolidin-4-One}-N6-(4-Nitrophenyl)-1,3,5-Triazine-2,4,6-Triamine Derivatives”
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Abstract
Saturated thiazole thiazolidinone, which has a carbonyl group on its fourth carbon, is regarded as a magic moiety that possesses nearly every kind of biological activity. It is a member of a significant class of heterocyclic compounds that have nitrogen and sulfur arranged in a five-member ring. Although there are several heterocyclic five-membered rings accessible, thiazolidinone has a wide range of biological functions. The current review covers all of the pharmacological activity associated with thiazolidinone, as well as future prospects. Using these reviews, we created a novel series of N2,N4-bis{2-(substitutedphenyl)-3-phenyl-1,3-thiazolidin-4-one}-N6-(4-nitrophenyl)-1,3,5-triazine-2,4,6-triamine derivatives generated by the reaction between N2,N4-bis(4-{[(substitutedphenyl)methylidene]amino} phenyl)-N6-(4-nitrophenyl)-1,3,5-triazine-2,4,6-triamine with thioglycolic acid and anhydrous zinc chloride in absolute ethanol. IR and NMR spectrum data, as well as element analysis, were used to describe the title compounds. Using the Cup-Borer technique, the antimicrobial properties of each chemical were examined.
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