PRECLINICAL ASSESSMENT OF NITROGEN-CONTAINING HETEROCYCLIC DERIVATIVES FOR BREAST CANCER INTERVENTION IN ANIMAL MODELS
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Abstract
Due to their inherent adaptability and distinctive physicochemical characteristics, the majority of heterocycle compounds and generally frequent heterocycle units found in the majority of medications now on the market have established them as genuine bases of medicinal chemistry. In addition to the medications that are now on the market, several more are being researched for their possible effectiveness in treating a variety of cancer. Specifically, these molecules inherent adaptability and dynamic core scaffold have been used in anticancer research. However, much like every other potential anticancer medication, heterocyclic compounds have drawbacks. We give a succinct summary of heterocyclic active compounds and families in this study, along with an emphasis on their primary medical uses.While examining the primary biochemical mechanisms of action, biological targets, structure-activity connections, and fundamental limitations in the utilisation of these substances, we have concentrate on those that are appropriate for cancer therapy.
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