Analysing The Effect Of Metal Complexes With Cefuroxime On Some Selected Bacteria
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Abstract
Silver and its compounds have long been utilized as antimicrobial agents in medicine. Silver sulfadiazine, a broad-spectrum antibiotic ointment, is widely used and effective against a wide range of bacteria and some yeast. Copper and its alloys possess natural antimicrobial properties. Ancient civilizations recognized and utilized the antimicrobial effects of copper long before the understanding of microbes in the nineteenth century. Mechanochemistry refers to reactions induced by the input of mechanical energy, typically involving solids, such as grinding in ball mills. It is gaining increased attention due to its ability to promote rapid and quantitative reactions between solids, often without the need for additional solvents. Historically, mechanochemistry has been a secondary approach to chemical synthesis, with solution-based methods being the default choice. Building upon our previous research on antibiotic resistance, this paper presents the impact of mechanochemically synthesized copper (II) and silver (I) complexes with cefuroxime on cephalosporin-resistant bacteria
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