In-Vitro Anthelmintic Potential Of Aqueous And Ethanolic Leaves And Roots Extracts Of Annona Muricata Against Earthworm

Abstract

Helminths or Parasitic worms of humans may cause chronic and sometimes deadly diseases considered as Neglected Tropical Diseases that infect around two billion people worldwide. Many of synthetic drugs available, for the treatment of various worm infection like alendazole, mebendazole and Ivermectn with more of adverse effects so the need of herbal formulations are essential for teating worm infections.Plants have been used as anthelmintic from ancient times. In our study we selected Annona muricata is well known traditional plant which is used for the treatement of many worm infection without adverse effect.Phytochemical screening was conducted using standard qualitative methods, it reveals that they were rich in secondary metabolite compounds such as alkaloids, saponins, tannins, flavonoids. The in-vitro anthelmintic activity was determined using earthworm. In this ethanolic exctract of 200 mg/ml concentration shows high anthelmintic activity when compared to other concentration of Annona Muricata leaves extract