Effect of Arginine and Citrulline Supplements on Cardiovascular Health and Sports Activities: A Narrative Review on Indian Perspective

Abstract

The use of nutritional supplements (NS) for improving sports performance and health has become popular, and Citrulline and Arginine are the most frequently used supplements in these fields. The global market for dietary supplements has had consistent growth in sales in the last decades. More than half of the individuals use dietary supplement extensively. Present systematic review aims to understand the role of dietary arginine and Citrulline supplements for cardiovascular health and sports performance. The complicated connection between the control of hemodynamic and overall homeostasis and Citrulline and Arginine have been established. Citrulline and Arginine play important role in protecting skeletal as well as health of cardiac muscles and structural integrity and also are involved in many metabolic processes. Arginine has successfully mediated the release of the synthesis of creatinine growth hormone, which significantly increases strength and muscle mass. Also, Arginine is necessary to produce nitric oxide, which promotes skeletal muscle growth and also enhances vascular function. Overall, arginine supplements have a reasonable positive effect on the health of the heart, muscles and bones, as well as on maintaining and escalate exercise capacity. On the other hand, Citrulline can possibly converted into Arginine in many cell types and can effectively make up shortages of Arginine and nitric oxide in various pathological and physiological circumstances. Moreover, Citrulline helps to detoxify ammonia while decreasing stress levels and fatigue and promoting performance of exercise. In order to increase and enhance human athletic activities, both arginine and Citrulline are required