A -Comprehensive Review of Integrating Medicinal Plant Constituents into Neurological Disorder Therapeutics

Abstract

Neurological diseases are disorders of the nervous system that gradually destroy the structure and function of the central or peripheral nervous system, affecting various parts of the brain. It affects a great number of individuals globally and is one of the main causes of death. Many disorders, particularly neurological diseases that have resisted conventional medical treatment have been treated with plant-based medications. Alzheimer's disease (AD) and Parkinson's disease (PD) are two of the most common neurological disorders (NDDs) and have a significant socioeconomic impact. Over many ages, people have looked to natural herbal remedies for a solution for non-divertic disorders. Numerous therapeutic plants and their secondary metabolites have been shown to be able to reduce the symptoms of NDDs. The main mechanisms that have been found to underpin phytochemicals' neuroprotective effects and potential to maintain neurological health as we age include inhibition of acetylcholinesterase and monoamine oxidase, antioxidant, anti-inflammatory, antithrombotic, and antiapoptotic properties, as well as neurotrophic activities. This article examines the molecular targets of some of the main herbal products that have the potential to cure non-communicable diseases (NDDs). Numerous investigations proved that plant extracts or their bioactive components were effective against non-disease-causing bacteria. Millions of individuals worldwide suffer from age-related NDDs, and herbal products may provide new avenues for therapy.