A Rare Case of High-Grade Urothelial Carcinoma of Renal Pelvis and Proximal Ureter with Divergent Differentiation

Abstract

Urothelial carcinoma with divergent differentiation is a variant of urothelial carcinoma and it is being increasingly recognized with the increase in awareness and advancement of immunohistochemistry. It is important to quantify the degrees of each differentiation for the prognosis and treatment of the patient. Here, we present a unique case of urothelial carcinoma of Renal pelvis with divergent differentiation showing urothelial, squamous, papillary, glandular, Rhabdoid and Plasmacytoid differentiation.