Hesperidin Loaded Liposomes for the Treatment of Diabetes and Hypertension

Abstract

Antimicrobial agents, cancer treatments, diabetes drugs, hypertension drugs, antifungal drugs, peptide hormones, enzymes, vaccines, and genetic materials are just some of the many drugs that Hesperidin loaded Liposomes (HLLs) have been shown to improve the delivery of in recent years. Liposomes can be broken down further into subgroups based on lamellarity, size, charge, and function due to variations in preparation processes and lipid compositions. They can be used for drug delivery via several routes of administration thanks to their adaptable behaviour, which is not dependent on their solubility. Liposomes loaded with hesperidin have the ability to target a chemical to specific tissues, potentially improving the therapeutic efficacy of several drugs. Medications' in vitro and in vivo efficacy can both be boosted by a drug delivery technology called hesperidin-loaded liposomes it can also decrease its toxicity, and increase its efficacy by delivering the molecule in a more regulated fashion. This article discusses analytical methods for managing physical, chemical, and biological characteristics in the production of various drugs, as well as ways for creating hesperidin-loaded liposomes. The main characteristics of the formation and manufacturing processes of liposome nanocarriers are covered in this article, with a focus on the structural characteristics and crucial factors that govern the development of acceptable and stable formulations. We detail the primary benefits (and drawbacks) of each method, as well as their suitability for mass industrial manufacturing.