Antibiotic resistance patterns in individuals with urinary tract infections: Bacterial profile

Abstract

Urinary tract infections (UTIs) are one of the most significant problems in medical science. Were also common bacterial infections that impact 150 million individuals each year globally. Serious consequences include frequent recurrences, pyelonephritis, kidney damage, premature delivery, and difficulties from repeated antibiotic treatment. The current study aims to identify the bacterial profile and antibiotic resistance trend among urinary tract infection patients. From October 2021 to April 2022, 185 patients with urinary tract infections were admitted to Rizgary Teaching Hospital in the Erbil-Kurdistan area. A systematic questionnaire was used to collect cultural and clinical information. Standard microbiological practices were used for culture and antibiotic resistance testing. According to the location of the infection, clinical specimens from the investigated patients showed a bacterial infection rate of 51.3%. Enterococcus faecalis (56.8%), Staphylococcus spp. (21%), Klebsiella pneumoniae (11.57%), Pseudomonas aeruginosa, and Streptococcus spp. (5.2%) were among the most common bacteria isolated. These bacterial isolates were antibiotic-resistant to various degrees. Many antibiotics, such as Cefotaxime, Nalidixic acid, and Amikacin, were resistant to Gram-negative bacteria, whereas Imipenem and Cefixime were sensitive. While Cefotaxime and Nalidixic Acid are resistant to Gram-positive bacteria, Imipenem, Ciprofloxacin, and Norfloxacin are highly sensitive. In conclusion, the significant prevalence of organisms and their resistance to widely used antibiotics raises questions about potential future treatments for these ailments.