Trace Elements In Health & Disease- A Boon In Disguise
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Abstract
Research on the existence of various elements in the universe has been extensive, but their role in the human body is not fully understood. About 98% of the human body mass consists of nine non-metallic elements, categorized into abundant and non-abundant/trace elements. Micronutrients, including trace elements, vitamins, and antioxidants, play a vital role in regenerative processes, coping with oxidative stress, and providing immunity against pathogens. Dental health is also dependent on these nutrients, which help in the production and development of oral mucosa, teeth, and surrounding tissues. The recommended intake of these nutrients remains variable due to factors such as geography, altitude, age, weight, physiological needs, pathological backlogs, and other recognizable/unrecognizable factors. Essential trace elements are broadly categorized into macro-elements, micro-elements or trace elements, probably essential elements, and potentially toxic elements. The current review focuses on the role of essential trace elements in maintaining oral health and their implications in various oral diseases and disorders.
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Chitturi R, Baddam VR, Prasad L, Prashanth L, Kattapagari K. A review on role of essential trace elements in health and disease. J Dr NTR Univ Heal Sci. 2015;4(2):75.
Xiu YM. Trace elements in health and diseases. Biomed Environ Sci. 1996;9(2-3):130- 136. http://www.ncbi.nlm.nih.gov/pubmed/8886323.
What Are Trace Elements? Osamu WADA. Vol 47.; 2004.
Mehri A. Trace Elements in Human Nutrition (II) - An Update. Int J Prev Med. 2020;11:2.
Istvan Pais, J. Benton Jones J. The Handbook of Trace Elements. CRC press; 1997
Sigel A, Sigel H, Sigel RKO, eds. Interrelations between Essential Metal Ions and Human Diseases. Vol 13. Dordrecht: Springer Netherlands; 2013.
Casamassimo PS, Flaitz CM, Hammersmith K, Sangvai S, Kumar A. Recognizing the Relationship Between Disorders in the Oral Cavity and Systemic Disease. Pediatr Clin North Am. 2018;65(5):1007-32.
Bhattacharya PT, Misra SR, Hussain M. Nutritional Aspects of Essential Trace Elements in Oral Health and Disease: An Extensive Review. Scientifica (Cairo). 2016.
Stohs SJ, Bagchi D. Oxidative mechanisms in the toxicity of metal ions. Free Radic Biol Med. 1995;18(2):321-36.
Report of a WHO expert Committee. Trace Elements in Human Nutrition. Geneva; 1973:532.
Frieden E. The evolution of metals as essential elements (with special reference to iron and copper). Adv Exp Med Biol. 1974;48:1-29.
Earl F. New perspectives on the essential trace elements. J Chem Educ. 1985;62:917- 23.
The Chemistry of Life: The Human Body | Live Science. https://www.livescience.com/3505-chemistry-life-human-body.html.
Chellan P, Sadler PJ. The elements of life and medicines. Philos Trans R Soc A Math Phys Eng Sci. 2015;373(2037).
Carbon Cycle - an overview | ScienceDirect Topics. https://www.sciencedirect.com/topics/immunology-and-microbiology/carbon-cycle.
Carbon Carbon Bond - an overview | ScienceDirect Topics. https://www.sciencedirect.com/topics/engineering/carbon-carbon-bond.
West TO, Marl G, Singh N, Bhaduri BL, Roddy AB. The human carbon budget: An estimate of the spatial distribution of metabolic carbon consumption and release in the United States. Biogeochemistry. 2009;94(1):29-41.
Luk K, Zhao IS, Yu OY, Zhang J, Gutknecht N, Chu CH. Effects of 10,600 nm Carbon Dioxide Laser on Remineralizing Caries: A Literature Review. Photobiomodulation, Photomedicine, Laser Surg. 2020;38(2):59-65.
Maiti D, Tong X, Mou X, Yang K. Carbon-Based Nanomaterials for Biomedical Applications: A Recent Study. Front Pharmacol. 2019;9:1401.
Gregorczyk-Maga I, Wachsmann A, Olszewska M, Partyka L. Exhaled carbon monoxide levels correlate with incidence of oral mucosal lesions independent of smoking status. Int J Environ Health Res. 2019;29(3):290-300.
Sharma A, Das J. Small molecules derived carbon dots: Synthesis and applications in sensing, catalysis, imaging, and biomedicine. J Nanobiotechnology. 2019;17(1):92.
Li Q, Zhou R, Xie Y, Li Y, Chen Y, Cai X. Sulphur‐doped carbon dots as a highly efficient nano‐photodynamic agent against oral squamous cell carcinoma. Cell Prolif. 2020;53(4).
Ge L, Yang M, Yang NN, Yin XX, Song WG. Molecular hydrogen: A preventive and therapeutic medical gas for various diseases. Oncotarget. 2017;8(60):102653-73.
MA Gillentine, LN Berry, RP Goin-Kochel, MA Ali, J Ge, D Guffey, JA Rosenfeld, V Hannig, et al. The cognitive and behavioral principles of individuals with CHRNA7 duplications. J Autism Dev Disord. 2017;47(3):549-62.
Yang M, Dong Y, He Q, et al. Hydrogen: A Novel Option in Human Disease Treatment. Oxid Med Cell Longev. 2020.
Williams AC, Ramsden DB. Hydrogen symbioses in evolution and disease. QJM. 2007;100(7):451-9.
Azuma T, Yamane M, Ekuni D, et al. Drinking hydrogen-rich water has additive effects on non-surgical periodontal treatment of improving periodontitis: A pilot study. Antioxidants. 2015;4(3):513-22.
Tomofuji T, Kawabata Y, Kasuyama K, et al. Effects of hydrogen-rich water on aging periodontal tissues in rats. Sci Rep. 2014;4.
Bruce Alberts, Dennis Bray, Julian Lewis, Martin Raff, Keith Roberts, James D Watson. Molecular Biology of the Cell - NCBI Bookshelf. 3rd ed. New York: Garland Science; 1994. https://www.ncbi.nlm.nih.gov/books/NBK20684/.
Wenger RH. Mammalian oxygen sensing, signalling and gene regulation. J Exp Biol. 2000;203(Pt 8):1253-63. http://www.ncbi.nlm.nih.gov/pubmed/10729275
Chen T, Zhou Y, Liu J, Xu B, Wu Z, Li D. Biological effects of hyperbaric oxygen on human severe periodontitis. Undersea Hyperb Med. 2002;29(3):159-66. https://europepmc.org/article/med/12670118.
Chen TL, Xu B, Liu JC, et al. Effects of hyperbaric oxygen on aggressive periodontitis and subgingival anaerobes in Chinese patients. J Indian Soc Periodontol. 2012;16(4):492.
Deepa D, Jain N. Applications of hyperbaric oxygen therapy in dentistry: A mini review. J Interdiscip Dent. 2014;4(1):27.
Jacobson AS, Buchbinder D, Hu K, Urken ML. Paradigm shifts in the management of osteoradionecrosis of the mandible. Oral Oncol. 2010;46(11):795-801.
Bocci VA. Scientific and medical aspects of ozone therapy. State of the art. Riv Ital di Ossigeno-Ozonoterapia. 2006;5(2):93-104.
Saini R. Ozone therapy in dentistry: A strategic review. J Nat Sci Biol Med. 2011;2(2):151-3.
Estrela C, Estrela CRA, Decurcio DA, Hollanda ACB, Silva JA. Antimicrobial efficacy of ozonated water, gaseous ozone, sodium hypochlorite and chlorhexidine in infected human root canals. Int Endod J. 2007;40(2):85-93.
Nagayoshi M, Fukuizumi T, Kitamura C, Yano J, Terashita M, Nishihara T. Efficacy of ozone on survival and permeability of oral microorganisms. Oral Microbiol Immunol. 2004;19(4):240-6.
Filippi A. The Influence of Ozonised Water on The Epithelial Wound Healing Process In The Oral Cavity. Clin Oral Surgery, Radiol Oral Med Univ Basel, Switzerland. 2011;1(14).
Rickard GD, Richardson RJ, Johnson TM, McColl DC, Hooper L. withdrawn: Ozone therapy for the treatment of dental caries. Cochrane database Syst Rev. 2019;2(2):CD004153.
Silva EJNL, Prado MC, Soares DN, Hecksher F, Martins JNR, Fidalgo TKS. The effect of ozone therapy in root canal disinfection: a systematic review. Int Endod J. 2020;53(3):317-332.
Mohammadi Z, Shalavi S, Soltani MK, Asgary S. A review of the properties and applications of ozone in endodontics: An update. Iran Endod J. 2013;8(2):40-3.
Barraza-Villarreal A, Escamilla-Nuñez MC, Hernández-Cadena L, et al. Elemental carbon exposure and lung function in schoolchildren from Mexico City. Eur Respir J. 2011;38(3):548-52.
Arita M, Nagayoshi M, Fukuizumi T, et al. Microbicidial efficacy of ozonated water against Candida albicans adhering to acrylic denture plates. Oral Microbiol Immunol. 2005;20(4):206-10.
Karapetian VE, Lowden E ZJ. Die Verwendung von Ozon in der PeriimplantitistherapieKlinische Studie. ZWR-Das Dtsch Zahnärzteblatt. 116(05):214-8.
Stübinger S, Sader R, Filippi A. The Use of Ozone in Dentistry and Maxillofacial Surgery: A Review. Vol 37.; 2006.
Ellis KJ, Yasumura S, Vartsky D, Vaswani AN, Cohn SH. Total body nitrogen in health and disease: effects of age, weight, height, and sex. J Lab Clin Med. 1982;99(6):917- 26.
Becker DE, Rosenberg M. Nitrous oxide and the inhalation anesthetics. Anesth Prog. 2008;55(4):124.
Mezger PR, Creugers NHJ. Titanium nitride coatings in clinical dentistry. J Dent. 1992;20(6):342-4.
Asrani S, Reddy P, Dhirawani R, Jain S, Pathak S, Asati P. Cryosurgery: A simple tool to address oral lesions. Contemp Clin Dent. 2018;9(5):S17-S22.
Farquhar WB, Edwards DG, Jurkovitz CT, Weintraub WS. Dietary sodium and health: More than just blood pressure. J Am Coll Cardiol. 2015;65(10):1042-50.
Spencer HR, Ike V, Brennan PA. Review: The use of sodium hypochlorite in endodontics - Potential complications and their management. Br Dent J. 2007;202(9):555-9.
Madeswaran S, Jayachandran S. Sodium bicarbonate: A review and its uses in dentistry. Indian J Dent Res. 2018;29(5):672.
Bhat SS, Ballal RK, Ramdas SS, Ballal S. Effect of Chewing Bicarbonate-containing Sugar-free Gum on the Salivary pH: An in vivo Study. Int J Clin Pediatr Dent. 2016;9(1):35-38.
Patel A, Amaechi BT, Brady C. Prevention and control of dental erosion: Gastroesophageal reflux disease management. In: Dental Erosion and Its Clinical Management. Springer International Publishing; 2015:203-24.
Kothiwale S, Kella M, Hombal L, Rathore A. Evaluation of Sodium Bicarbonate as an Adjunct to Non-Surgical Periodontal Therapy and Its Effect on Oxidative Stress: A Clinico-Biochemical Study.; 2014. www.symbiosisonline.orgwww.symbiosisonlinepublishing.com.
de Sousa FACG, Paradella TC, Koga-Ito CY, Jorge AOC. Effect of sodium bicarbonate on Candida albicans adherence to thermally activated acrylic resin. Braz Oral Res. 2009;23(4):381-5.
Myneni SR. Effect of baking soda in dentifrices on plaque removal. J Am Dent Assoc. 2017;148(11):S4-S9.
Hashemi A, Bahrololoumi Z, Khaksar Y, Saffarzadeh N, Neamatzade H, Foroughi E. Mouth-rinses for the prevention of chemotherapy induced oral mucositis in children: a systematic review. Iran J Pediatr Hematol Oncol. 2015;5(2):106-12.
Ezalia E, R IE, Elizabeth G, et al. No 主観的健康感を中心とした在宅高齢者におけ る 健康関連指標に関する共分散構造分析. Orphanet J Rare Dis. 2020;21(1):1- 9.
Van Den Broek AMWT, Feenstra L, De Baat C. A review of the current literature on management of halitosis. Oral Dis. 2008;14(1):30-9.
Schwarz F, Becker K, Renvert S. Efficacy of air polishing for the non-surgical treatment of peri-implant diseases: A systematic review. J Clin Periodontol. 2015;42(10):951-9.
Petersilka GJ, Bell M, Häberlein I, Mehl A, Hickel R, Flemmig TF. In vitro evaluation of novel low abrasive air polishing powders. J Clin Periodontol. 2003;30(1):9-13.
Li Y. Stain removal and whitening by baking soda dentifrice: A review of literature. J Am Dent Assoc. 2017;148(11):S20-S26.
Guideline: Potassium Intake for Adults and Children. Gebeva: World Health Organization;2012. Introduction.
Orchardson R, Gillam DG, Orchardson R. The Efficacy of Potassium Salts as Agents for Treating Dentin Hypersensitivity.
Lynch MC, Perfekt R, McGuire JA, et al. Potassium oxalate mouthrinse reduces dentinal hypersensitivity: A randomized controlled clinical study. J Am Dent Assoc. 2018;149(7):608-18.
Docimo R, Montesani L, Maturo P, et al. Desensitizing efficacy of a new toothpaste containing 5.5% potassium citrate: a 4-week clinical study. Am J Dent. 2007;20(4):209- 11
Schmidt L, Dimitrov A, Kemnitz E. A new approach to prepare nanoscopic rare earth metal fluorides: The fluorolytic sol–gel synthesis of ytterbium fluoride. Chem Commun. 2014;50(50):6613-6.
Peckham S, Awofeso N. Water fluoridation: a critical review of the physiological effects of ingested fluoride as a public health intervention. Scientific World Journal. 2014;2014:293019.
Wong MCM, Clarkson J, Glenny AM, et al. Cochrane reviews on the benefits/risks of fluoride toothpastes. J Dent Res. 2011;90(5):573-9.
Fluoride: Topical and Systemic Supplements. https://www.ada.org/en/membercenter/oral-health-topics/fluoride-topical-and-systemic-supplements.
Calcium - Health Professional Fact Sheet. https://ods.od.nih.gov/factsheets/CalciumHealthProfessional/#en1.
Calcium I of M (US) C to RDRI for VD and, Ross AC, Taylor CL, Yaktine AL, Valle HB Del. Dietary Reference Intakes for Calcium and Vitamin D. National Academies Press; 2011.
Dawson-Hughes B, Dallal GE, Krall EA, Sadowski L, Sahyoun N, Tannenbaum S. A Controlled Trial of the Effect of Calcium Supplementation on Bone Density in Postmenopausal Women. N Engl J Med. 1990;323(13):878-83.
Krall EA. Calcium and Oral Health. In: Calcium in Human Health. Humana Press; 2007:319-25.
Chen M, Pan A, Malik VS, Hu FB. Effects of dairy intake on body weight and fat: A meta-analysis of randomized controlled trials. Am J Clin Nutr. 2012;96(4):735-47.
Moyer VA. Vitamin D and calcium supplementation to prevent fractures in adults: U.S. preventive services task Force recommendation statement. Ann Intern Med. 2013;158(9):691-6.
JOHANSEN E. Nutrition, diet, and calcium metabolism in dental health. Am J Public Health Nations Health. 1960;50(8):1089-96.
Eshghi A, Kowsari-Isfahan R, Rezaiefar M, Razavi M, Zeighami S. Effect of iron containing supplements on rats’ dental caries progression. J Dent (Tehran). 2012;9(1):14-9.
DeLoughery TG. Iron Deficiency Anemia. Med Clin North Am. 2017;101(2):319-32.
Alfthan G, Eurola M, Ekholm P, et al. Effects of nationwide addition of selenium to fertilizers on foods, and animal and human health in Finland: From deficiency to optimal selenium status of the population. J Trace Elem Med Biol. 2015;31:142-7.
Ventura M, Melo M, Carrilho F. Selenium and thyroid disease: From pathophysiology to treatment. Int J Endocrinol. 2017:1-12.