Synthesis And Anti-Microbial Activity Of 1,2,4-Triazole Derivatives

Abstract

The research work was aimed to design and synthesize new Schiff’s bases and Amine derivatives of triazole and to evaluate them for their possible biological activities mainly anti-bacterial and anti-fungal activity. In the present work total 21 compounds were synthesized from three parent compounds parent-1, parent-2, parent-3. These parent compounds were used as nucleus for the synthesis of various Schiff base derivatives like 1 (a-g), 2(a-g), 3(a-g). All synthesized compounds were identified based on M.P. range, IR, NMR and all compounds were evaluated for anti- bacterial and anti-fungal activity.