Polymeric Patches For Transdermal Delivery Of Nsaids: Formulation Strategies And Evaluation Techniques
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Abstract
Transdermal drug delivery offers numerous advantages over conventional oral and parenteral routes, particularly for non-steroidal anti-inflammatory drugs (NSAIDs). Polymeric patches have emerged as promising platforms for delivering NSAIDs transdermally due to their ease of application, improved patient compliance, and sustained drug release profiles. This review comprehensively examines the formulation strategies and evaluation techniques employed in the development of polymeric patches for transdermal delivery of NSAIDs. Various polymeric systems, including matrix, reservoir, and drug-in-adhesive formulations, are discussed along with their advantages and limitations. Evaluation techniques encompassing drug release kinetics, skin permeation studies, adhesive properties, and mechanical characteristics are critically analyzed to ensure the efficacy and safety of polymeric patch formulations.
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