Synthesis of PBAT/CNT Bone Scaffold

Abstract

Bone marrow produces blood cells and supports the immune system in our body but due to some reasons like diseases, injuries, medical treatment damages bone marrow. Traditional bone marrow regeneration methods, like transplantation, face limitations due to donor availability and immune rejection. Researchers are exploring bio scaffolds for functional tissue regeneration. The bio scaffolds are synthesized by using PBAT and CNT at different ratios. PBAT/CNT (0.5%) and PBAT/CNT (5%). This can be done in 4 steps (1) PBAT synthesis (2) g-PBAT synthesis (3) Amine CNT (4) Final Product PBAT/CNT. Characterized was done using FTIR, NMR, mechanical strength, DSC, & SEM. FTIR intensity at
1741 shows PBAT grafted to maleic acid and 3498 peak shows NH stretching, NMR explain about the structure. PBAT/CNT 3.5% got high tensile strength. DSC could calculate the melting point. SEM gives images of pore size, PBAT, is a biodegradable polymer through a process of hydrolysis, it is mimicking bone marrow's extracellular matrix, providing support, growth, and promoting biocompatibility. Carbon nanotubes (CNTs) are incorporated into PBAT offering high mechanical strength, electrical conductivity, and cell adhesion, making them ideal for tissue engineering applications. Biodegradability of PBAT prevents surgical removal, and the bio scaffold gradually breaks down over time, promoting
regenerated tissue development.