Comparative Analysis of Morphological Changes Occurring in The Thymus in Mild Traumatic Brain Injury

Authors

  • Akhmedova Shakhlo Malikovna Bukhara State Medical Institute., Uzbekistan.
  • Badridinova Barno Kamolidinovna Bukhara State Medical Institute., Uzbekistan.
  • Shodieva Nilufar O’tkirjonovna Bukhara State Medical Institute., Uzbekistan.
  • Zhorakulova Zebiniso Axtamovna Bukhara State Medical Institute., Uzbekistan.
  • Khudoyorova Dilnoza Rizayevna Bukhara State Medical Institute., Uzbekistan.

DOI:

https://doi.org/10.17762/jaz.v44iS6.2105

Keywords:

Traumatic Brain Injury, The Immune System, Autoimmune Reactions; Gassali Cells, Inflammation Fat Metamorphosis

Abstract

In the experiments, 34 white thoroughbred rats aged 1,3,6 months were used. These are white non-breeding rats of both sexes weighing on average about 250-300 g. The rats were fixed on a self-propelled vehicle with manual control, and in the moving vehicle, the experimental rats approached the wooden barrier and hit them on the forehead, which led to brain injury. The speed of the car was 6.7 km per hour. In the course of experiments on a traffic accident, 30 rats survived and 4 rats died. In general, i.e. macroscopic view of the thymus of 1,3,6-month-old white rats, changes are observed depending on the month, varying degrees of morphological changes in the state of fatty metamorphosis in the thymus cortex, consisting of lymphoid cells (thymocytes), blood vessels, Hassali cells and epithelial cells.

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Published

2023-11-24

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