Quantitative Analysis of Phytoconstituents of Hydroalcoholic Extract of Carica Papaya Leaf

Abstract

Carica papaya (C. papaya) leaves have been used in folk medicine for centuries. Several reports are available for use of Carica papaya leaves in increasing blood platelet count in dengue hemorrhagic fever. Recent studies also reported that Carica papaya leaves exhibits anti-tumor activity and immunomodulatory effects. Papaya leaf extract is reported to contain carbohydrates, amino acids, sterols, saponin glycosides, iridoids, flavonoids, phenolics, anthraquionones, triterpenes and alkaloids. The present investigation demonstrates the concentration of secondary metabolites in the hydroalcoholic extract of Carica papaya leaves. The total phenolics, total alkaloid and total flavonoid content were calculated by Folin–Ciocalteu colorimetric method, Bromocresol green colorimetric method and aluminum chloride colorimetric method respectively.