ACUTE HEMORRHAGIC STROKE PROGNOSTIC MARKERS BASED ON SERUM FERRITIN LEVELS: A COMPREHENSIVE CROSS-SECTIONAL STUDY

Abstract

Accurate prognostic markers are essential for the efficient management of acute haemorrhagic stroke, a serious cerebrovascular event. In order to establish serum ferritin as a prognostic biomarker, this study investigates the connection between acute haemorrhagic stroke patients' admission serum ferritin levels and outcomes.

Materials and Methodology: A cross-sectional study with 72 patients who had an acute haemorrhagic stroke was carried out, and clinical characteristics, neuroimaging results, and serum ferritin levels were examined. The Modified Rankin Scale (mRS) and Glasgow Coma Scale (GCS) scores were used to assess functional outcomes. Studies using correlation and regression statistics were conducted.

Results: When compared to patients who had positive outcomes (150.6 ng/ml), patients with negative outcomes had considerably higher blood ferritin levels (337.8 ng/ml). Elevated ferritin had a positive (r=0.756) and a negative (r=-0.709) correlation with mRS and GCS scores, respectively. Serum ferritin was found by regression analysis to be an independent predictor of decline or death (OR=1.024, p < 0.0001).

Conclusion: Severe outcomes in acute haemorrhagic stroke are correlated with elevated serum ferritin levels at admission. A potential independent predictive factor that could help with clinical decisions is serum ferritin. Interventions that aim to raise ferritin levels can potentially enhance patient outcomes, according to future research.