A Study On Assessment Of Clinical Profile And Quality Of Life Of Acute Decompensated Heart Failure In Tertiary Care Hospital

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Vankodoth Sireesha
Faiqua Fatima
Shafeen Sultana
Shiva Sai Kumar
Rohith Kumar. A
K Malikarjuna Rao
Rama Rao Tatikonda

Abstract

Heart failure is a prevalent chronic disease worldwide, and acute decompensated heart failure (ADHF) is characterized by sudden or gradual onset of heart failure symptoms requiring unplanned medical attention. The study aims to examine the    clinical presentation, and Quality of life of ADHF in a tertiary care hospital, along with the demographic characteristics. The study highlights the impact of ADHF on physical and emotional well-being and help identify potential risk factors and complications. It was a prospective observational study conducted at a tertiary care hospital for a period of 6 months and 75 Patients were included. Patients were evaluated clinically and with laboratory tests. Data were collected and analysed. The majority of patients were female (84%).  A combination of Diabetes and Hypertension (25.3%) was the most common past medical illness found in the patients. The most common presenting symptom was shortness of breath 42(56%). Ischemic stroke was the most common complication (20%). The overall score of Qol was found to be mostly between 51-75 (61.4%) and the mean was 52.81.


In conclusion the findings will provide valuable insights into the clinical characteristics and QoL of ADHF patients. Periodic QoL assessments could contribute to better patient management and overall outcomes in ADHF. However, as the study is conducted in a single center with a limited sample size, the results should be interpreted with caution and cannot be generalised to the broader population.

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How to Cite
Vankodoth Sireesha, Faiqua Fatima, Shafeen Sultana, Shiva Sai Kumar, Rohith Kumar. A, K Malikarjuna Rao, & Rama Rao Tatikonda. (2024). A Study On Assessment Of Clinical Profile And Quality Of Life Of Acute Decompensated Heart Failure In Tertiary Care Hospital. Journal of Advanced Zoology, 45(3), 789–796. https://doi.org/10.53555/jaz.v45i3.4464
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Articles
Author Biographies

Vankodoth Sireesha

Assistant professor, CMR College of pharmacy, Hyderabad, Telangana.

Faiqua Fatima

Pharm D intern, CMR College of Pharmacy, Hyderabad, Telangana. 

Shafeen Sultana

Pharm D intern, CMR College of Pharmacy, Hyderabad, Telangana.

Shiva Sai Kumar

Pharm D intern, CMR College of Pharmacy, Hyderabad, Telangana.

Rohith Kumar. A

Student , Pharm D Department, CMR College of pharmacy , Hyderabad, Telangana.

K Malikarjuna Rao

Student , Pharm D Department, CMR College of pharmacy , Hyderabad, Telangana.

Rama Rao Tatikonda

Professor, Principal, Ph. D, CMR College of Pharmacy, Hyderabad. Telangana

References

Abotalebidariasari, G., Memarian, R., Vanaki, Z., Kazemnejad, A., &Naderi, N.(2017) Self-Care Agency Power Components Among Patients with Heart Failure: A Qualitative Directed Content Analysis Based on the Orem Self-Care Theory. Crit Care Nurs J.

Gheorghiade M, Zannad F, Sopko G, Klein L, Pina IL, Konstam MA, et al. (2005) Acute heart failure syndromes: current state and framework for future research. Circulation.

O'Connor CM, Stough WG, Gallup DS, Hasselblad V, Gheorghiade M 2005. Demographics, clinical characteristics, and outcomes of patients hospitalized for decompensated heart failure: observations from the IMPACT-HF registry. J Card Fail.

Montera MW, Pereira SB, Colafranceschi AS, Almeida DR, Tinoco EM, Rocha RM, et al. 2012 Summary of the II Brazilian Guideline update on Acute Heart Failure 2009/2011. Arq Bras Cardiol.

Einstein (Sao Paulo). 2013 Jul-Sep; 11(3): 383–391.Decompensated heart failure. .Decompensated heart failure.

Yancy CW, Jessup M, Bozkurt B, et al. 2017 ACC/AHA/HFSA focused update of the 2013 ACCF/AHA guideline for the management of heart failure: a report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Failure Society of America. J Am Coll Cardiol. 2017;70(6):776-803. doi:10.1016/j.jacc.2017.04.025.

Gheorghiade M, Zannad F, Sopko G, et al. Acute heart failure syndromes: current state and framework for future research. Circulation. 2005;112(25):3958-3968.

doi:10.1161/CIRCULATIONAHA.105.590091.

Ponikowski P, Voors AA, Anker SD, et al. 2016 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure. Eur Heart J. 2016;37(27):2129-2200. doi:10.1093/eurheartj/ehw128.

Tsutamoto T, Wada A, Maeda K, et al. Attenuation of compensation of endogenous cardiac natriuretic peptide system in chronic heart failure: prognostic role of plasma brain natriuretic peptide concentration in patients with chronic symptomatic left ventricular dysfunction. Circulation 1997 https://doi.org/.

Joseph SM, Cedars AM, Ewald GA, Geltman EM, Mann DL. Acute decompensated heart failure: contemporary medical management. Tex Heart Inst J. 2009;36(6):510-20. Erratum in: Tex Heart Inst J. 2010;37(1):135. Dosage error in article text. PMID: 20069075; PMCID: PMC2801958.

Watson RD, Gibbs CR, Lip GY. ABC of heart failure. Clinical features and complications. BMJ. 2000 Jan 22;320(7229):236-9. doi: 10.1136/bmj.320.7229.236. PMID: 10642237; PMCID: PMC1117436.

Association of religiosity and spirituality with quality of life in patients with cardiovascular disease: a systematic review. Abu HO, Ulbricht C, Ding E, Allison JJ, Salmoirago-Blotcher E, Goldberg RJ, Kiefe CI. Qual Life Res. 2018;27:2777–2797.

Effect of multimorbidity on quality of life in adult with cardiovascular disease: a cross-sectional study. Shad B, Ashouri A, Hasandokht T, Rajati F, Salari A, Naghshbandi M, Mirbolouk F. Health Qual Life Outcomes. 2017;15:240.

Savarese G, Lund LH. Global public health burden of heart failure.Card Fail Rev. 2017; 3:7–11. doi: 10.15420/cfr.2016:25:2.

Ezekowitz JA, O’Meara E, McDonald MA, Abrams H, Chan M, Ducharme A, Giannetti N, Grzeslo A, Hamilton PG, Heckman GA, et al. 2017 comprehensive update of the Canadian Cardiovascular Society guidelines for the management of heart failure.Can J Cardiol. 2017; 33:1342–1433. doi: 10.1016/j.cjca.2017.08.022.

Ponikowski P, Voors AA, Anker SD, Bueno H, Cleland JG, Coats AJ, Falk V, González-Juanatey JR, Harjola VP, Jankowska EA, et al; Authors/Task Force Members; Document Reviewers. 2016 ESC guidelines for the diagnosis and treatment of acute and chronic heart failure: the task force for the diagnosis and treatment of acute and chronic heart failure of the European Society of Cardiology (ESC): developed with the special contribution of the Heart Failure Association (HFA) of the ESC.Eur J Heart Fail. 2016; 18:891–975. doi: 10.1002/ejhf.592.

Kelkar AA, Spertus J, Pang P, Pierson RF, Cody RJ, Pina IL, Hernandez A, Butler J. Utility of patient-reported outcome instruments in heart failure.JACC Heart Fail. 2016; 4:165–175. doi: 10.1016/j.jchf.2015.10.015.

Mastenbroek MH, Versteeg H, Zijlstra W, Meine M, Spertus JA, Pedersen SS. Disease-specific health status as a predictor of mortality in patients with heart failure: a systematic literature review and meta-analysis of prospective cohort studies.Eur J Heart Fail. 2014; 16:384–393. doi: 10.1002/ejhf.55.

Khan MS, Kalogeropoulos AP, Butler J. Variation in placebo effect on health-related quality of life in heart failure (from the TOPCAT trial).Am J Cardiol. 2020; 125:82–86. doi: 10.1016/j.amjcard.2019.09.037.

Filippatos G, Maggioni AP, Lam CSP, Pieske-Kraigher E, Butler J, Spertus J, Ponikowski P, Shah SJ, Solomon SD, Scalise AV, et al. Patient-reported outcomes in the Soluble Guanylate Cyclase Stimulator in Heart Failure Patients With Preserved Ejection Fraction (SOCRATES-PRESERVED) study.Eur J Heart Fail. 2017; 19:782–791. doi: 10.1002/ejhf.800.

Alsawas M, Wang Z, Murad MH, Yousufuddin M. Gender disparities among hospitalised patients with acute myocardial infarction, acute decompensated heart failure or pneumonia: retrospective cohort study. BMJ Open. 2019 Jan 21;9(1):e022782. doi: 10.1136/bmjopen-2018-022782. PMID: 30670508; PMCID: PMC6347873.

Azad N, Lemay G. Management of chronic heart failure in the older population. J Geriatr Cardiol. 2014 Dec;11(4):329-37. doi: 10.11909/j.issn.1671-5411.2014.04.008. PMID: 25593582; PMCID: PMC4292097.

Kim W, Kim EJ. Heart Failure as a Risk Factor for Stroke. J Stroke. 2018 Jan;20(1):33-45. doi: 10.5853/jos.2017.02810. Epub 2018 Jan 31. PMID: 29402070; PMCID: PMC5836579.

Petrie JR, Guzik TJ, Touyz RM. Diabetes, Hypertension, and Cardiovascular Disease: Clinical Insights and Vascular Mechanisms. Can J Cardiol. 2018 May;34(5):575-584. doi: 10.1016/j.cjca.2017.12.005. Epub 2017 Dec 11. PMID: 29459239; PMCID: PMC5953551.

Inamdar AA, Inamdar AC. Heart Failure: Diagnosis, Management and Utilization. J Clin Med. 2016 Jun 29;5(7):62. doi: 10.3390/jcm5070062. PMID: 27367736; PMCID: PMC4961993.

Iguchi M, Kato T, Yaku H, Morimoto T, Inuzuka Y, Tamaki Y, Ozasa N, Yamamoto E, Yoshikawa Y, Kitai T, Hamatani Y, Yamashita Y, Masunaga N, Ogawa H, Ishii M, An Y, Taniguchi R, Kato M, Takahashi M, Jinnai T, Ikeda T, Nagao K, Kawai T, Komasa A, Nishikawa R, Kawase Y, Morinaga T, Kawato M, Seko Y, Toyofuku M, Furukawa Y, Ando K, Kadota K, Abe M, Akao M, Sato Y, Kuwahara K, Kimura T. Ischemic Stroke in Acute Decompensated Heart Failure: From the KCHF Registry. J Am Heart Assoc. 2021 Nov 2;10(21):e022525. doi: 10.1161/JAHA.121.022525. Epub 2021 Oct 23. PMID: 34689603; PMCID: PMC8751829.

Alharbi M, Alharbi F, AlTuwayjiri A, Alharbi Y, Alhofair Y, Alanazi A, AlJlajle F, Khalil R, Al-Wutayd O. Assessment of health-related quality of life in patients with heart failure: a cross-sectional study in Saudi Arabia. Health Qual Life Outcomes. 2022 Aug 30;20(1):128. doi: 10.1186/s12955-022-02040-7. PMID: 36042486; PMCID: PMC9425984.