Effectiveness Of Topical Application Of Honey On Radiation Induced Mucositis In Patients Undergoing Radiation Therapy At Selected Hospital In Vadodara.
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Abstract
Background: Most patients with oral cancer receive chemo radiotherapy with or without surgery for treatment and develop oral mucositis, a debilitating adverse. Currently, there is no standard regimen for the management of radiation-induced mucositis. This study aims to evaluate the effect of honey on radiation-induced mucositis.
Methods: Quasi experimental study of 50 cancer patient was undertaken in chosen areas and 25 patients were in experimental group and 25 patients were in control group. The data were obtained from patients via face-to-face interviews using a pretested questionnaire, and the data were analyzed using SPSS version 25.0 software
Result: In experimental group the mean pretest assessment value was 1.2 and the standard deviation was 0.4 and in the control group the mean pretest assessment was 1.8 and the standard deviation was0.8. The p-value (0.0044) p<0.05 significant. That is honey application was effective to reducing the oral mucositis among patients undergoing radiation therapy in post-test. Demographic variables Age, Gender, food habits, smoking, alcohol, tobacco chewing, chewing battle leaves, education level and profession had shown no statistically significant association with the pretest grades of oral mucositis. P<0.005
Conclusion: Natural honey can be an excellent treatment for radiation-induced oral mucositis. Honey may be a simple, potent, and inexpensive medication that is widely available, and it may be a more effective therapeutic agent in the treatment of radiation mucositis
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References
Sonis ST. Oral mucositis with cancer treatment. Journal of Supportive Oncology, 2014;2:3-8.
Bernhoft CH, Skaug N. Oral results in edentulous irradiation individuals. International Journal of Oral Surgery. 1985;14:416-27.
M. Motallebnejad, S. Akram, A. Moghadamnia, Z. Moulana, and S. Omidi. A randomised clinical trial assessing the impact of topical pure honey treatment on radiation-induced mucositis. Journal of Contemporary Dental Practise. 2008;3:40-7.
Biswal BM, Zakaria A, and Ahmad NM. The use of honey as a topical treatment for radiation mucositis. Cancer Support Care, 11:242-8, 2003.
Subrahmanyam, M. A prospective randomised clinical and histological trial of honey and silver sulfadiazine in the treatment of superficial burn wounds. Burns. 1998;24:157-61.
Cooper, R.A., Molan, P.C., Krishnamoorthy, L., and Harding, K.G. Manuka honey was utilised to treat a stubborn surgical wound. 2001;20:758-9. Eur J Clin Microbiol Infect Dis.
R. Meredith et al. Sucralfate for radiation mucositis: results of a double-blind randomized trial Int. J. Radiat. Oncol. Biol. Phys. (1997)
P. Plevova Prevention and treatment of chemotherapy and radiotherapy induced oral mucositis: a review.
Bergman, J. Yanai, J. Weiss, D. Bell, and M. P. David. Topical honey use speeds up wound healing.A model for animals. Am J Surg., 145:374-6, 1983.